Age
Item
over the age of 21
boolean
C0001779 (UMLS CUI [1])
Informant Evaluation Functioning
Item
will have an informant/study partner who will be able to provide independent evaluation of functioning
boolean
C1550484 (UMLS CUI [1,1])
C1261322 (UMLS CUI [1,2])
C0205245 (UMLS CUI [1,3])
Alzheimer's Disease Atypical | Difficulty using language | Logopenic progressive aphasia | Visuospatial deficit | Perceptual disturbance | Posterior cortical atrophy
Item
must fulfill clinical diagnostic criteria for atypical ad, and hence should either have a chief complaint of difficulty with language and fulfill criteria for logopenic variant of primary progressive aphasia, or present with visuospatial/perceptual deficits and fulfill criteria for posterior cortical atrophy
boolean
C0002395 (UMLS CUI [1,1])
C0205182 (UMLS CUI [1,2])
C0564213 (UMLS CUI [2])
C4274665 (UMLS CUI [3])
C2921138 (UMLS CUI [4])
C0233746 (UMLS CUI [5])
C4275079 (UMLS CUI [6])
Primary Language Spoken English | Bilingual person Language primary English
Item
speaks english as their primary language (including bilingual patients whose primary language is english)
boolean
C4331028 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0682128 (UMLS CUI [2,1])
C1717991 (UMLS CUI [2,2])
C0376245 (UMLS CUI [2,3])
MRI | PET scan
Item
agrees to and is eligible to undergo mri and pet scanning
boolean
C0024485 (UMLS CUI [1])
C0032743 (UMLS CUI [2])
Childbearing Potential Pregnancy Test
Item
if woman of child bearing age, must agree to pregnancy test no more than 48 hours before the pet scans
boolean
C3831118 (UMLS CUI [1,1])
C0032976 (UMLS CUI [1,2])
Comorbidity | Traumatic Brain Injury | Cerebrovascular accident | Developmental Disabilities
Item
subjects with concurrent illnesses that could account for the presenting syndrome, such as traumatic brain injury, strokes or developmental syndromes
boolean
C0009488 (UMLS CUI [1])
C0876926 (UMLS CUI [2])
C0038454 (UMLS CUI [3])
C0008073 (UMLS CUI [4])
Neurodegenerative Disorder | Dementia of the Alzheimer's type
Item
subjects meeting criteria for another neurodegenerative disease, particularly typical alzheimer's dementia
boolean
C0524851 (UMLS CUI [1])
C0854732 (UMLS CUI [2])
Pregnancy | Postpartum Period | Breast Feeding
Item
women that are pregnant or post-partum and breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0086839 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
Medical contraindication MRI | Metal foreign body in head | Artificial cardiac pacemaker | Claustrophobia Severe | Condition Interferes with Imaging of brain | MISCELLANEOUS STRUCTURAL ABNORMALITIES | Hematoma, Subdural | Neoplasms, Intracranial
Item
subjects will also be excluded if mri is contraindicated (metal in head, cardiac pace maker, e.t.c.), if there is severe claustrophobia, and if there are conditions that may confound brain imaging studies (e.g. structural abnormalities, including subdural hematoma or intracranial neoplasm)
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0561024 (UMLS CUI [2])
C0030163 (UMLS CUI [3])
C0008909 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0348080 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0203860 (UMLS CUI [5,3])
C0333310 (UMLS CUI [6])
C0018946 (UMLS CUI [7])
C1527390 (UMLS CUI [8])
informant Lacking | Consent Absent Research | Completion Absent Component Clinical Trial | Neurologic Examination | Other Coding | MRI | PET with concurrent CT using C-PiB
Item
subjects will also be excluded if they do not have an informant, do not consent to research or do not complete all components of the study (neurological exam, neuropsychometric tests, mri, pib pet)
boolean
C1550484 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
C1511481 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0035168 (UMLS CUI [2,3])
C0205197 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C1705248 (UMLS CUI [3,3])
C0008976 (UMLS CUI [3,4])
C0027853 (UMLS CUI [4])
C3846158 (UMLS CUI [5])
C0024485 (UMLS CUI [6])
C4271886 (UMLS CUI [7])