Age
Item
1. men and women over 18 year-old.
boolean
C0001779 (UMLS CUI [1])
Sinus rhythm
Item
2. in sinus rhythm.
boolean
C0232201 (UMLS CUI [1])
Heart valve disease | Coronary Artery Disease | Requirement Cardiac Surgery Extracorporeal Circulation
Item
3. affected by valve disease, isolated or associated with coronary artery disease, satisfying requirements for heart surgery under extracorporeal circulation.
boolean
C0018824 (UMLS CUI [1])
C1956346 (UMLS CUI [2])
C1514873 (UMLS CUI [3,1])
C0018821 (UMLS CUI [3,2])
C0015354 (UMLS CUI [3,3])
Childbearing Potential Contraceptive methods
Item
4. women of childbearing potential must use effective contraception and they must commit to maintain it throughout the study.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Urgent surgical procedure
Item
1. urgent surgery.
boolean
C2188405 (UMLS CUI [1])
Operative Surgical Procedure Due to Endocarditis
Item
2. surgery due to endocarditis.
boolean
C0543467 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0014118 (UMLS CUI [1,3])
Episode Previous Atrial Fibrillation | Sinus rhythm | Hospital admission
Item
3. patients with previous episodes of atrial fibrillation, although they are in sinus rhythm at hospital admission.
boolean
C0332189 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0004238 (UMLS CUI [1,3])
C0232201 (UMLS CUI [2])
C0184666 (UMLS CUI [3])
Adrenergic beta-1 Receptor Antagonists
Item
4. treatment with beta-blockers at time of randomization
boolean
C0304516 (UMLS CUI [1])
Left Ventricular Dysfunction Severe | Left ventricular ejection fraction
Item
5. severe left ventricular dysfunction with ventricular ejection fraction under 30%.
boolean
C0242698 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0428772 (UMLS CUI [2])
NSAIDs chronic | Adrenal Cortex Hormones chronic
Item
6. chronic using of nsaids and / or corticosteroids at time of randomization
boolean
C0003211 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0001617 (UMLS CUI [2,1])
C0205191 (UMLS CUI [2,2])
Thyroid Disease Uncontrolled
Item
7. uncontrolled thyroid disease.
boolean
C0040128 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Liver disease | Chronic liver disease
Item
8. active liver disease and / or history of previous chronic liver disease.
boolean
C0023895 (UMLS CUI [1])
C0341439 (UMLS CUI [2])
Alcoholic Intoxication, Chronic
Item
9. alcoholism.
boolean
C0001973 (UMLS CUI [1])
Predisposing Factors | Adverse effects Statins
Item
10. predisposing factors to statins adverse effects:
boolean
C0032946 (UMLS CUI [1])
C0879626 (UMLS CUI [2,1])
C0360714 (UMLS CUI [2,2])
Transaminases increased
Item
increased transaminase levels at baseline (x3 normal value).
boolean
C0438717 (UMLS CUI [1])
Kidney Failure | Creatinine measurement, serum
Item
renal failure (creatinine levels over 2 mg/dl).
boolean
C0035078 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Myopathy Etiology Any
Item
previous diagnosis of myopathy of any etiology.
boolean
C0026848 (UMLS CUI [1,1])
C0015127 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
Hypersensitivity Atorvastatin calcium | Hypersensitivity Lactose Monohydrate
Item
11. known hypersensitivity to calcium atorvastatin and / or lactose monohydrate
boolean
C0020517 (UMLS CUI [1,1])
C0286650 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C1658042 (UMLS CUI [2,2])
Childbearing Potential Pregnancy test positive
Item
12. in women of childbearing age, positive pregnancy test the day of inclusion in the study.
boolean
C3831118 (UMLS CUI [1,1])
C0240802 (UMLS CUI [1,2])
Informed Consent Lacking
Item
13. not signed informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
Study Protocol Comprehension Unable
Item
14. inability to understand objectives of the study.
boolean
C2348563 (UMLS CUI [1,1])
C0162340 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Exclusion Criteria | Clinical Trial Started
Item
exclusion criteria of the study once started:
boolean
C0680251 (UMLS CUI [1])
C0008976 (UMLS CUI [2,1])
C1272689 (UMLS CUI [2,2])
Withdrawal Informed Consent
Item
withdrawal of patient's consent.
boolean
C2349954 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
Liver Laboratory parameters Modification | Transaminases increased | Creatine kinase measurement | Suggestive of Adverse effects Statins
Item
modification in liver laboratory parameters (transaminases above three times normal value) and / or creatine-fosfokinase level suggesting adverse effects of statins.
boolean
C0023884 (UMLS CUI [1,1])
C0022877 (UMLS CUI [1,2])
C0449381 (UMLS CUI [1,3])
C0392747 (UMLS CUI [1,4])
C0438717 (UMLS CUI [2])
C0201973 (UMLS CUI [3])
C0332299 (UMLS CUI [4,1])
C0879626 (UMLS CUI [4,2])
C0360714 (UMLS CUI [4,3])