Laryngeal Squamous Cell Carcinoma TNM clinical staging | ECOG performance status
Item
stage iii, iva, or ivb squamous cell carcinoma of the larynx, with ecog performance status 0-2
boolean
C0280324 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C1520224 (UMLS CUI [2])
Age
Item
patients 18 years or older.
boolean
C0001779 (UMLS CUI [1])
Patient Appropriate Organ Preserving | Chemotherapy Head and neck | Radiotherapy to head and neck
Item
determined by the treating physician to be a candidate for organ preserving, concurrent standard chemotherapy and radiation therapy to the head and neck with definitive intent.
boolean
C0030705 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
C0178784 (UMLS CUI [1,3])
C0728887 (UMLS CUI [1,4])
C0392920 (UMLS CUI [2,1])
C0460004 (UMLS CUI [2,2])
C3888854 (UMLS CUI [3])
Prior radiation therapy Head and neck | Prior Chemotherapy
Item
prior radiation therapy to the head and neck prior chemotherapy within the past 5 years
boolean
C0279134 (UMLS CUI [1,1])
C0460004 (UMLS CUI [1,2])
C1514457 (UMLS CUI [2])
HIV Protease Inhibitor | Disease TNM clinical staging | Pregnancy | Breast Feeding | HIV Infection
Item
previous therapy with a human immunodeficiency virus (hiv) protease inhibitor presence of t4b disease,precluding organ preservation pregnant or lactating patients. patients with known hiv disease.
boolean
C3536912 (UMLS CUI [1])
C0012634 (UMLS CUI [2,1])
C3258246 (UMLS CUI [2,2])
C0032961 (UMLS CUI [3])
C0006147 (UMLS CUI [4])
C0019693 (UMLS CUI [5])
Antiretroviral therapy Interaction Nelfinavir
Item
these patients have a high probability of treatment with anti-retroviral therapy which may interact with the nelfinavir.
boolean
C1963724 (UMLS CUI [1,1])
C0687133 (UMLS CUI [1,2])
C0525005 (UMLS CUI [1,3])
Absolute neutrophil count | Platelet Count measurement | Serum creatinine raised | Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
absolute neutrophil count 1500 per mm3 platelet count 100,000 per mm3 serum creatinine 1.5 times the upper limit of normal serum ast or alt 2 times the upper limit of normal
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0700225 (UMLS CUI [3])
C0151904 (UMLS CUI [4])
C0151905 (UMLS CUI [5])
Serum bilirubin measurement | Weight loss Percentage Timespan | Etiology Malignant Neoplasm | Wasting Syndrome | Distant metastasis | Pharmaceutical Preparations Contraindicated Nelfinavir
Item
serum bilirubin 1.2 mg/dl weight loss of 10% over the past 6 months which is due to tumor wasting syndrome distant metastases patients receiving the following drugs that are contraindicated with nfv will be excluded.
boolean
C0428441 (UMLS CUI [1])
C1262477 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0872291 (UMLS CUI [2,3])
C0015127 (UMLS CUI [3,1])
C0006826 (UMLS CUI [3,2])
C0043046 (UMLS CUI [4])
C1269798 (UMLS CUI [5])
C0013227 (UMLS CUI [6,1])
C1444657 (UMLS CUI [6,2])
C0525005 (UMLS CUI [6,3])