Schizophrenia
Item
patients with a diagnosis of sz, according to dsm-iv criteria, for at least one year, evaluated with scid/p
boolean
C0036341 (UMLS CUI [1])
PANSS Clinical Classification | Antipsychotic Agents
Item
a minimum panss total score of 55 (indicating moderate severity, due to ongoing ap treatment) .
boolean
C4086747 (UMLS CUI [1])
C0040615 (UMLS CUI [2])
Clinical global impression scale
Item
a minimum cgi-s score of 4
boolean
C3639708 (UMLS CUI [1])
Age
Item
age between 18 and 45 years
boolean
C0001779 (UMLS CUI [1])
Disease length
Item
a disorder duration of no longer than 10 years
boolean
C0872146 (UMLS CUI [1])
Childbearing Potential Pregnancy test negative
Item
women of childbearing age must test negative for pregnancy at the time of enrolment.
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Patients All
Item
all patients must:
boolean
C0030705 (UMLS CUI [1,1])
C0444868 (UMLS CUI [1,2])
Antipsychotic Agents Generation second | Antipsychotic Agents Dose Therapeutic | Antipsychotic Agents Quantity | Change in drug dosage Absent
Item
be on a therapeutic dose of a sga (or a maximum 2 sgas) with no major dose changes for at least 4 weeks.
boolean
C0040615 (UMLS CUI [1,1])
C0079411 (UMLS CUI [1,2])
C0205436 (UMLS CUI [1,3])
C0040615 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0302350 (UMLS CUI [2,3])
C0040615 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0420247 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
Informed Consent
Item
have the ability to provide informed consent
boolean
C0021430 (UMLS CUI [1])
Use of Nasal spray
Item
be able to use a nasal spray
boolean
C1524063 (UMLS CUI [1,1])
C2825048 (UMLS CUI [1,2])
Residence Nearby
Item
reside in the service catchment area
boolean
C0237096 (UMLS CUI [1,1])
C1706276 (UMLS CUI [1,2])
Substance Dependence Absent
Item
show evidence of no alcohol or substance dependence in the last year
boolean
C0038580 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Mental Retardation
Item
diagnosis of mental retardation
boolean
C0025362 (UMLS CUI [1])
Organic mental disorder
Item
diagnosis of organic mental disorder
boolean
C0029227 (UMLS CUI [1])
Clozapine Response Absent
Item
history of no response to treatment with clozapine
boolean
C0009079 (UMLS CUI [1,1])
C1704632 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Oxytocin allergy | Hypersensitivity Oxytocin vehicle
Item
history of hypersensitivity to oxt or vehicle
boolean
C0571729 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C0030095 (UMLS CUI [2,2])
C0042444 (UMLS CUI [2,3])
Substance Dependence
Item
alcohol or substance dependence in the last year
boolean
C0038580 (UMLS CUI [1])
Allergic rhinitis
Item
presence of, or history of clinically significant allergic rhinitis as assessed by the treating clinician
boolean
C2607914 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
being pregnant or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Birth | Breast Feeding
Item
having given birth in the past 6 months or breast-feeding in the past 3 months
boolean
C0005615 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Low-level literacy | Lacking Able to read Consent Form | Consent Form Comprehension Unable
Item
low literacy as indicated by an inability to read and understand the consent form
boolean
C1401894 (UMLS CUI [1])
C0332268 (UMLS CUI [2,1])
C0586740 (UMLS CUI [2,2])
C0009797 (UMLS CUI [2,3])
C0009797 (UMLS CUI [3,1])
C0162340 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])