Age
Item
males or females, aged >= 18 years at time of consent.
boolean
C0001779 (UMLS CUI [1])
Arthritis, Psoriatic
Item
have a diagnosis of psoriatic arthritis (psa) of >= 6 months
boolean
C0003872 (UMLS CUI [1])
Psoriatic Arthritis Classification Criteria
Item
meet the classification criteria of psa (caspar) at time of screening
boolean
C0003872 (UMLS CUI [1,1])
C0008902 (UMLS CUI [1,2])
C0243161 (UMLS CUI [1,3])
Requirement Absent Non-Biologic DMARD
Item
must not have been adequately treated with a a traditional non-biologic disease modifying anti-rheumatic drug (dmard).
boolean
C1514873 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C4054347 (UMLS CUI [1,3])
Methotrexate | leflunomide | Sulfasalazine
Item
concurrent treatment with methotrexate, leflunomide, or sulfasalazine allowed and required
boolean
C0025677 (UMLS CUI [1])
C0063041 (UMLS CUI [2])
C0036078 (UMLS CUI [3])
Requirement Absent TNF inhibitors biologic
Item
must not have taken a biologic tumour necrosis factor inhibitor
boolean
C1514873 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C3653350 (UMLS CUI [1,3])
C0205460 (UMLS CUI [1,4])
Swollen joint count | Tender joint count
Item
must have 3 or more swollen joints and 3 or more tender joints
boolean
C0451521 (UMLS CUI [1])
C0451530 (UMLS CUI [2])
Psoriasis Skin lesion
Item
must have active psoriasis skin lesions
boolean
C0033860 (UMLS CUI [1,1])
C0037284 (UMLS CUI [1,2])
Psoriasis Without Plaque | Erythrodermic psoriasis | Guttate psoriasis | Pustular psoriasis | Exception Psoriasis of nail
Item
have non-plaque forms of psoriasis, eg erythrodermic, guttate or pustular, with the exception of nail psoriasis which is allowed
boolean
C0033860 (UMLS CUI [1,1])
C0332288 (UMLS CUI [1,2])
C0920235 (UMLS CUI [1,3])
C0748052 (UMLS CUI [2])
C0343052 (UMLS CUI [3])
C0152081 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C0406322 (UMLS CUI [5,2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Absent
Item
pregnant or breast feeding, females of child-bearing potential not using highly effective contraception
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Congestive heart failure New York Heart Association Classification
Item
new york heart association class iii and iv congestive heart failure
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Hypersensitivity Biological agents | Infusion related reaction Biological agents
Item
history of hypersensitivity or infusion reaction to biologic agents
boolean
C0020517 (UMLS CUI [1,1])
C0005515 (UMLS CUI [1,2])
C0948715 (UMLS CUI [2,1])
C0005515 (UMLS CUI [2,2])
HIV Infection | Hepatitis B | Hepatitis C | Chronic infectious disease
Item
infection with hiv, hepatitis b virus, hepatitis c virus, or other chronic infection
boolean
C0019693 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019196 (UMLS CUI [3])
C0151317 (UMLS CUI [4])