Gender | Age
Item
men 18 years of age or older
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Adenocarcinoma of prostate
Item
diagnosis of adenocarcinoma of the prostate, confirmed by h.l. moffitt cancer center review
boolean
C0007112 (UMLS CUI [1])
Prostate carcinoma Untreated
Item
no prior treatment for prostate cancer
boolean
C0600139 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
ECOG performance status
Item
eastern cooperative oncology group (ecog) performance status of 0 or1
boolean
C1520224 (UMLS CUI [1])
Prostate carcinoma TNM clinical staging
Item
prostate cancer clinical stage t2a and below
boolean
C0600139 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
Prostate specific antigen measurement
Item
psa <10 ng/ml (this will be the prostatic specific antigen (psa) level prompting the initial prostate biopsy)
boolean
C0201544 (UMLS CUI [1])
Size of prostate TRUS
Item
prostate size <60 cc on transrectal ultrasound
boolean
C1287816 (UMLS CUI [1,1])
C0373345 (UMLS CUI [1,2])
Biopsy Parameters | Status pre- Enrollment | Core biopsy Quantity Minimum | Primary Gleason pattern | Neoplasm Unilateral | Neoplasm Percentage Core biopsy | Core biopsy Positive Quantity Gleason pattern
Item
pre-enrollment biopsy parameters (as per h.l. moffitt c.c. review): minimum of 10 biopsy cores; no primary pattern biopsy gleason grade 4 or 5; unilateral cancer (only right-sided or left-sided, not bilateral); no more than 1 core with 50% cancer; no more than 4 cores with positive biopsies with gleason pattern 3 + 3 and no more than 2 cores with positive biopsies containing gleason pattern 3 + 4.
boolean
C0005558 (UMLS CUI [1,1])
C0449381 (UMLS CUI [1,2])
C0332152 (UMLS CUI [2,1])
C1516879 (UMLS CUI [2,2])
C1318309 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C1524031 (UMLS CUI [3,3])
C1273604 (UMLS CUI [4])
C0027651 (UMLS CUI [5,1])
C0205092 (UMLS CUI [5,2])
C0027651 (UMLS CUI [6,1])
C0439165 (UMLS CUI [6,2])
C1318309 (UMLS CUI [6,3])
C1318309 (UMLS CUI [7,1])
C1514241 (UMLS CUI [7,2])
C1265611 (UMLS CUI [7,3])
C1273606 (UMLS CUI [7,4])
Gender | Age
Item
men less than 18 years of age
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Medically unfit Anesthesia
Item
medically unfit for anesthesia
boolean
C3841806 (UMLS CUI [1,1])
C0002903 (UMLS CUI [1,2])
Histology | Exception Adenocarcinoma
Item
histology other than adenocarcinoma
boolean
C0344441 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0001418 (UMLS CUI [2,2])
Biopsy Inclusion criteria failed
Item
biopsy does not meet inclusion criteria
boolean
C0005558 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0231175 (UMLS CUI [1,3])
Gender Hormone manipulation | Androgen Antagonists | LHRH Agonist | 5-alpha Reductase Inhibitors
Item
men who have received any hormonal manipulation (antiandrogens; luteinizing hormone releasing hormone (lhrh) agonist; 5-alpha-reductase inhibitors) within the previous 6 months
boolean
C0079399 (UMLS CUI [1,1])
C0586971 (UMLS CUI [1,2])
C0002842 (UMLS CUI [2])
C1518041 (UMLS CUI [3])
C2936788 (UMLS CUI [4])