Parkinson Disease
Item
diagnosis of idiopathic pd
boolean
C0030567 (UMLS CUI [1])
Off Treatment hours/day
Item
daily "off" time ≥ 4 hours
boolean
C1518544 (UMLS CUI [1,1])
C0556974 (UMLS CUI [1,2])
Levodopa unchanged | Dopamine Agonists unchanged
Item
no changes in levodopa or any other dopaminergic medications expected during the course of the study
boolean
C0023570 (UMLS CUI [1,1])
C0442739 (UMLS CUI [1,2])
C0178601 (UMLS CUI [2,1])
C0442739 (UMLS CUI [2,2])
Cognitive ability Montreal cognitive assessment
Item
will be screened for cognitive ability (montreal cognitive assessment score of ≥ 24) prior to enrollment
boolean
C0392334 (UMLS CUI [1,1])
C3496286 (UMLS CUI [1,2])
SIBO Screening
Item
will be screened for presence of sibo prior to enrollment
boolean
C2959722 (UMLS CUI [1,1])
C0220908 (UMLS CUI [1,2])
Gastrointestinal Disease Changing Absorption | Gastrointestinal Disease Interferes with Research results | Absence Relationship Parkinson Disease | Achlorhydria | Systemic disease Changing Absorption | Systemic disease Interferes with Research results
Item
any comorbid non-pd-associated gastrointestinal (e.g., achlorhydria) or systemic diseases that may alter absorption or confound the study results
boolean
C0017178 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
C0237442 (UMLS CUI [1,3])
C0017178 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
C0332197 (UMLS CUI [3,1])
C0439849 (UMLS CUI [3,2])
C0030567 (UMLS CUI [3,3])
C0001075 (UMLS CUI [4])
C0442893 (UMLS CUI [5,1])
C0392747 (UMLS CUI [5,2])
C0237442 (UMLS CUI [5,3])
C0442893 (UMLS CUI [6,1])
C0521102 (UMLS CUI [6,2])
C0683954 (UMLS CUI [6,3])
Exposure to Proton Pump Inhibitors | Exposure to Immunosuppressive Agents | Pharmaceutical Preparations Affecting Gastrointestinal Motility | Prokinetic Agent | Anticholinergic Agents | Tricyclic Antidepressive Agents | Antibiotics | Pharmaceutical Preparations Affecting Intestinal Flora | Laxatives
Item
exposure to proton pump inhibitors, immunosuppressive drugs, medications that affect gi motility (such as prokinetics, anticholinergics, and tricyclic antidepressants), antibiotics or any other drugs that affect the intestinal flora (such as laxatives) within a month prior to enrollment.
boolean
C0332157 (UMLS CUI [1,1])
C0358591 (UMLS CUI [1,2])
C0332157 (UMLS CUI [2,1])
C0021081 (UMLS CUI [2,2])
C0013227 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C0017184 (UMLS CUI [3,3])
C1268865 (UMLS CUI [4])
C0242896 (UMLS CUI [5])
C0003290 (UMLS CUI [6])
C0003232 (UMLS CUI [7])
C0013227 (UMLS CUI [8,1])
C0392760 (UMLS CUI [8,2])
C2985398 (UMLS CUI [8,3])
C0282090 (UMLS CUI [9])
Deep Brain Stimulation | Ablation Neurosurgical Procedure
Item
prior deep brain stimulation or ablative functional neurosurgery.
boolean
C0394162 (UMLS CUI [1])
C0547070 (UMLS CUI [2,1])
C0524850 (UMLS CUI [2,2])
Hypersensitivity Rifaximin
Item
prior allergy to rifaximin
boolean
C0020517 (UMLS CUI [1,1])
C0073374 (UMLS CUI [1,2])
Pregnancy | Breast Feeding | Pregnancy, Planned
Item
women who are pregnant, lactating, or plan to become pregnant.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])