Ovarian Carcinoma | Fallopian Tube Carcinoma | Carcinoma of peritoneum | Patients Unresponsive to Platinum | Patients Resistant to Platinum | Chemotherapy Quantity Recurrent disease
Item
ovarian, fallopian tube or peritoneal carcinoma: both platinum refractory and platinum resistant patients, who have received ≥ 1 lines of chemotherapy for relapsed disease (i.e., ≥2 lines of chemotherapy in total).
boolean
C0029925 (UMLS CUI [1])
C0238122 (UMLS CUI [2])
C0948303 (UMLS CUI [3])
C0030705 (UMLS CUI [4,1])
C0205269 (UMLS CUI [4,2])
C0032207 (UMLS CUI [4,3])
C0030705 (UMLS CUI [5,1])
C0332325 (UMLS CUI [5,2])
C0032207 (UMLS CUI [5,3])
C0392920 (UMLS CUI [6,1])
C1265611 (UMLS CUI [6,2])
C0277556 (UMLS CUI [6,3])
Endometrial Carcinoma | Chemotherapy Quantity | Recurrent disease TNM clinical staging | Advanced disease TNM clinical staging
Item
endometrial carcinoma: patients must have received ≥ 1 line of chemotherapy for relapsed or advanced (stage iv, iiic) disease.
boolean
C0476089 (UMLS CUI [1])
C0392920 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0277556 (UMLS CUI [3,1])
C3258246 (UMLS CUI [3,2])
C0679246 (UMLS CUI [4,1])
C3258246 (UMLS CUI [4,2])
Cervix carcinoma | Chemotherapy Quantity | Recurrent disease | Advanced disease TNM clinical staging
Item
cervical carcinoma: patients must have received ≥ 1 lines of chemotherapy for relapsed or advanced (stage ivb) disease.
boolean
C0302592 (UMLS CUI [1])
C0392920 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0277556 (UMLS CUI [3])
C0679246 (UMLS CUI [4,1])
C3258246 (UMLS CUI [4,2])
Breast Carcinoma | Breast adenocarcinoma | Neoplasm Metastasis Inappropriate Excision | Advanced disease Locally Inappropriate Excision | Neoplasm Metastasis Inappropriate Curative treatment | Advanced disease Locally Inappropriate Curative treatment
Item
breast cancer: adenocarcinoma of the breast with metastatic or locally advanced disease not amenable to curative resection or any other curative treatment.
boolean
C0678222 (UMLS CUI [1])
C0858252 (UMLS CUI [2])
C0027627 (UMLS CUI [3,1])
C1548788 (UMLS CUI [3,2])
C0728940 (UMLS CUI [3,3])
C0679246 (UMLS CUI [4,1])
C1517927 (UMLS CUI [4,2])
C1548788 (UMLS CUI [4,3])
C0728940 (UMLS CUI [4,4])
C0027627 (UMLS CUI [5,1])
C1548788 (UMLS CUI [5,2])
C1273390 (UMLS CUI [5,3])
C0679246 (UMLS CUI [6,1])
C1517927 (UMLS CUI [6,2])
C1548788 (UMLS CUI [6,3])
C1273390 (UMLS CUI [6,4])
Breast Carcinoma | Hormone Therapy Quantity Neoplasm Metastasis | Chemotherapy Quantity Neoplasm Metastasis
Item
breast cancer: patients must have received ≥ 1 line of endocrine treatment or chemotherapy for metastatic disease as applicable for the respective breast cancer subtype.
boolean
C0678222 (UMLS CUI [1])
C0279025 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0027627 (UMLS CUI [2,3])
C0392920 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0027627 (UMLS CUI [3,3])
Breast Carcinoma | Triple Negative Breast Neoplasms | Hormone receptor positive tumor | Oestrogen receptor positive breast cancer | Progesterone receptor positive tumor | HER2 negative carcinoma of breast
Item
breast cancer: patient must have either triple negative cancer or be hormone receptor positive (i.e., er+ and/or pr+) and her2 negative.
boolean
C0678222 (UMLS CUI [1])
C3539878 (UMLS CUI [2])
C1563119 (UMLS CUI [3])
C2938924 (UMLS CUI [4])
C1562928 (UMLS CUI [5])
C2316304 (UMLS CUI [6])
Measurable Disease | Evaluable Disease | Exception Radiation Field CT | Exception Radiation Field MRI
Item
must have either measurable disease (recist 1.1) or evaluable disease outside irradiated field on ct/mri. a rise in ca-125 or other tumor marker alone is not sufficient.
boolean
C1513041 (UMLS CUI [1])
C1516986 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C1882536 (UMLS CUI [3,2])
C0040405 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C1882536 (UMLS CUI [4,2])
C0024485 (UMLS CUI [4,3])
ECOG performance status
Item
ecog performance status of 0-1.
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy of at least 12 weeks.
boolean
C0023671 (UMLS CUI [1])
Able to swallow Oral medication | Ability Retain Oral medication
Item
able to swallow and retain oral medication.
boolean
C2712086 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
C0085732 (UMLS CUI [2,1])
C0333118 (UMLS CUI [2,2])
C0175795 (UMLS CUI [2,3])
Intestinal Obstruction Complete | Partial bowel obstruction
Item
evidence of complete or partial bowel obstruction.
boolean
C0021843 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C1328480 (UMLS CUI [2])
Malignant Neoplasms Gynecological Without Epithelium | Neuroendocrine Tumors
Item
gynecological cancer: all non-epithelial cancers of the ovary, fallopian tube, peritoneum, endometrium or cervix as well as neuro-endocrine tumors are excluded.
boolean
C0006826 (UMLS CUI [1,1])
C0018417 (UMLS CUI [1,2])
C0332288 (UMLS CUI [1,3])
C0014609 (UMLS CUI [1,4])
C0206754 (UMLS CUI [2])
Therapeutic radiology procedure
Item
radiation (except planned or ongoing palliative radiation to bone outside of the region of measurable disease) ≤ 3 weeks prior to c1d1.
boolean
C1522449 (UMLS CUI [1])
Chemotherapy | Immunotherapy | Cancer treatment Systemic
Item
chemotherapy, immunotherapy or systemic anticancer therapy ≤ 3 weeks prior to c1d1.
boolean
C0392920 (UMLS CUI [1])
C0021083 (UMLS CUI [2])
C0920425 (UMLS CUI [3,1])
C0205373 (UMLS CUI [3,2])