Age
Item
age ≥18 and ≤ 90 at the time of informed consent.
boolean
C0001779 (UMLS CUI [1])
Arthritis of knee Moderate Symptomatic
Item
subjects with symptomatic moderate arthritis of the knee defined as per
boolean
C0240111 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
C0231220 (UMLS CUI [1,3])
Kellgren-Lawrence score | Bilateral arthritis of knees | Enrollment Knee Single
Item
kellgren-lawrence grade ii or iii (appendix b). subjects with bilateral arthritis of the knee will also be recruited, but only one knee will be enrolled into the study.
boolean
C3177117 (UMLS CUI [1])
C3864080 (UMLS CUI [2])
C1516879 (UMLS CUI [3,1])
C0022742 (UMLS CUI [3,2])
C0205171 (UMLS CUI [3,3])
Able to walk Unaided Feet Quantity
Item
ability to walk 50 feet unassisted.
boolean
C2712089 (UMLS CUI [1,1])
C0439846 (UMLS CUI [1,2])
C0347981 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
Lequesne index
Item
lequesne's functional index score greater than 7 points
boolean
C0451257 (UMLS CUI [1])
Inflammatory disorder Systemic | Inflammatory Bowel Disease | Psoriasis | Eczema
Item
subjects with systemic inflammatory conditions such as inflammatory bowel disease, psoriasis, eczema, and others
boolean
C1290884 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0021390 (UMLS CUI [2])
C0033860 (UMLS CUI [3])
C0013595 (UMLS CUI [4])
Arthritis of knee Seropositive | Arthritis of knee Seronegative | Rheumatoid Arthritis | Ankylosing spondylitis
Item
subjects with seropositive or sero-negative inflammatory arthritis of the knee such as rheumatoid arthritis or ankylosing spondylitis.
boolean
C0240111 (UMLS CUI [1,1])
C0521143 (UMLS CUI [1,2])
C0240111 (UMLS CUI [2,1])
C0521144 (UMLS CUI [2,2])
C0003873 (UMLS CUI [3])
C0038013 (UMLS CUI [4])
Hormone replacement therapy
Item
subjects taking hormone replacement therapy
boolean
C0282402 (UMLS CUI [1])
Intraarticular injection of corticosteroids
Item
intra-articular corticosteroid injections 3 weeks prior to enrollment.
boolean
C2064783 (UMLS CUI [1])
Fish oils allergy
Item
hypersensitivity to fish oil.
boolean
C0571871 (UMLS CUI [1])
Non-steroidal anti-inflammatory drug allergy | Liver function tests abnormal finding | Renal function tests abnormal | Peptic Ulcer | Upper gastrointestinal hemorrhage | Congestive heart failure | Hypertensive disease | Blood pressure determination | Malignant Neoplasms | Hyperkalemia
Item
hypersensitivity to non-steroidal anti-inflammatory drugs, abnormal liver of kidney function tests, history of peptic ulceration and upper gastrointestinal hemorrhage, congestive heart failure, hypertension (bp>140/90), cancer and hyperkalemia.
boolean
C0570537 (UMLS CUI [1])
C0151766 (UMLS CUI [2])
C0236151 (UMLS CUI [3])
C0030920 (UMLS CUI [4])
C0041909 (UMLS CUI [5])
C0018802 (UMLS CUI [6])
C0020538 (UMLS CUI [7])
C0005824 (UMLS CUI [8])
C0006826 (UMLS CUI [9])
C0020461 (UMLS CUI [10])
Complete Blood Count Abnormal result Major | Blood Coagulation Disorders | Hematological Disease | Nervous system disorder
Item
major abnormal findings on complete blood count, history of coagulopathies, hematological or neurological disorders.
boolean
C0009555 (UMLS CUI [1,1])
C0459424 (UMLS CUI [1,2])
C0205164 (UMLS CUI [1,3])
C0005779 (UMLS CUI [2])
C0018939 (UMLS CUI [3])
C0027765 (UMLS CUI [4])
Heavy alcohol consumption Drinks U/day | Pregnancy | Breast Feeding | Pregnancy, Planned
Item
high alcohol intake (>2 standard drinks per day). pregnant, breastfeeding or planning to become pregnant during the study
boolean
C2030272 (UMLS CUI [1,1])
C0001967 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
C0032961 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
C0032992 (UMLS CUI [4])
Operative Surgical Procedures Expected | Knee affected
Item
subjects awaiting surgery on the affected knee within three months.
boolean
C0543467 (UMLS CUI [1,1])
C1517001 (UMLS CUI [1,2])
C0022742 (UMLS CUI [2,1])
C1314939 (UMLS CUI [2,2])
Vitamins Dose Stable allowed | Supplements Dose Stable allowed
Item
consumption of any other vitamins/supplements will be allowed, provided the dose is not increased, and same brand is continued with. also, the regimen should not contain the same active compounds tested in the prn joint health formula product.
boolean
C0042890 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0683607 (UMLS CUI [1,4])
C0242295 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0683607 (UMLS CUI [2,4])
Vitamins Introduction | Supplements Introduction
Item
vitamins/supplements cannot be introduced during a subject's participation in the study.
boolean
C0042890 (UMLS CUI [1,1])
C1293116 (UMLS CUI [1,2])
C0242295 (UMLS CUI [2,1])
C1293116 (UMLS CUI [2,2])