Informed Consent
Item
subjects must be willing to give written informed consent.
boolean
C0021430 (UMLS CUI [1])
Adult | Age | Racial group | Patient on waiting list Transplantation of liver
Item
adult subjects 18-75 years of age of any race or gender who are listed for liver transplantation.
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0034510 (UMLS CUI [3])
C0422768 (UMLS CUI [4,1])
C0023911 (UMLS CUI [4,2])
Consideration Sleeve gastrectomy
Item
for consideration of sleeve gastrectomy placement patients must meet the following criteria:
boolean
C0518609 (UMLS CUI [1,1])
C3160799 (UMLS CUI [1,2])
Obesity Class | Body mass index | Comorbidity Relationship Severe Obesity | Sleep study Consistent with Obstructive Sleep Apnea | Epworth Sleepiness Scale Questionnaire | Polysomnography: respiratory disturbance index | Apneic episodes hour of sleep | Cardiovascular Disease | Cerebrovascular accident | Myocardial Infarction | Stable angina | Angina, Unstable | Coronary Artery Bypass Surgery | Refractory hypertension | Blood pressure determination | Systolic Pressure | Diastolic blood pressure | Antihypertensive Agents Quantity Class Different | Diabetes Mellitus, Non-Insulin-Dependent | Insulin | Oral hypoglycemic | Glucose measurement, fasting
Item
1. class iii obesity (bmi ≥ 40 kg/m2); or 2. class ii obesity (bmi 35-39.9 kg/m2 in conjunction with any of the following severe obesity related co-morbidities): i. obstructive sleep apnea defined as a formal sleep study consistent with this diagnosis with a) an epworth sleepiness scale ≥ 6 and b) polysomnography with respiratory disturbance index ≥ 10 and/or apneic episodes per hour of sleep; or ii. cardiovascular disease defined as prior history of stroke, myocardial infarction, stable or unstable angina pectoris, or prior coronary artery bypass); or iii. medically refractory hypertension defined as blood pressure greater than 140 mmhg systolic and/or 90 mmhg diastolic despite concurrent use of 3 anti-hypertensive agents of different classes iv. type 2 diabetes mellitus, defined as individuals taking insulin or oral hypoglycemic agents or who have a fasting glucose > 126 mg/dl
boolean
C0028754 (UMLS CUI [1,1])
C0456387 (UMLS CUI [1,2])
C1305855 (UMLS CUI [2])
C0009488 (UMLS CUI [3,1])
C0439849 (UMLS CUI [3,2])
C0028756 (UMLS CUI [3,3])
C0162701 (UMLS CUI [4,1])
C0332290 (UMLS CUI [4,2])
C0520679 (UMLS CUI [4,3])
C3541276 (UMLS CUI [5])
C2111853 (UMLS CUI [6])
C0003578 (UMLS CUI [7,1])
C2937255 (UMLS CUI [7,2])
C0007222 (UMLS CUI [8])
C0038454 (UMLS CUI [9])
C0027051 (UMLS CUI [10])
C0340288 (UMLS CUI [11])
C0002965 (UMLS CUI [12])
C0010055 (UMLS CUI [13])
C0860493 (UMLS CUI [14])
C0005824 (UMLS CUI [15])
C0871470 (UMLS CUI [16])
C0428883 (UMLS CUI [17])
C0003364 (UMLS CUI [18,1])
C1265611 (UMLS CUI [18,2])
C0456387 (UMLS CUI [18,3])
C1705242 (UMLS CUI [18,4])
C0011860 (UMLS CUI [19])
C0021641 (UMLS CUI [20])
C0359086 (UMLS CUI [21])
C0202045 (UMLS CUI [22])
Weight loss Effort Attempt | Weight loss Attempt failed | Diet therapy | Exercise | Lifestyle changes | Pharmaceutical Preparations
Item
2. have attempted (and failed) previous weight loss efforts over at least a three month period with diet, exercise, lifestyle changes or medications.
boolean
C1262477 (UMLS CUI [1,1])
C0015264 (UMLS CUI [1,2])
C1516084 (UMLS CUI [1,3])
C1262477 (UMLS CUI [2,1])
C1516084 (UMLS CUI [2,2])
C0231175 (UMLS CUI [2,3])
C0012159 (UMLS CUI [3])
C0015259 (UMLS CUI [4])
C0870811 (UMLS CUI [5])
C0013227 (UMLS CUI [6])
Comprehension Risks and Benefits Operative Surgical Procedures | Comprehension Side effects Procedure
Item
3. show understanding of the risks and benefits of surgery and side effects of the procedure.
boolean
C0162340 (UMLS CUI [1,1])
C0687742 (UMLS CUI [1,2])
C0543467 (UMLS CUI [1,3])
C0162340 (UMLS CUI [2,1])
C0879626 (UMLS CUI [2,2])
C0184661 (UMLS CUI [2,3])
Commitment Lifestyle changes
Item
4. be committed to lifestyle changes. all patients will be evaluated by the transplant psychologist as well as the bariatric surgery psychologist prior to consideration for study enrollment to ensure appropriate psychological motivation.
boolean
C0870312 (UMLS CUI [1,1])
C0870811 (UMLS CUI [1,2])
Absence Medical condition Preventing Operative Surgical Procedures | Absence Emotional or mental condition Preventing Operative Surgical Procedures | Coronary Artery Disease Severe | Schizophrenia untreated | Substance Use Disorders | Compliance behavior Lacking Medical care
Item
5. do not have any medical, psychiatric or emotional condition that would prohibit surgery (e.g. severe irreversible coronary artery disease, untreated schizophrenia, active substance abuse, and/or noncompliance with previous medical care)
boolean
C0332197 (UMLS CUI [1,1])
C3843040 (UMLS CUI [1,2])
C1292733 (UMLS CUI [1,3])
C0543467 (UMLS CUI [1,4])
C0332197 (UMLS CUI [2,1])
C3843038 (UMLS CUI [2,2])
C1292733 (UMLS CUI [2,3])
C0543467 (UMLS CUI [2,4])
C1956346 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0036341 (UMLS CUI [4,1])
C0332155 (UMLS CUI [4,2])
C0038586 (UMLS CUI [5])
C1321605 (UMLS CUI [6,1])
C0332268 (UMLS CUI [6,2])
C0496675 (UMLS CUI [6,3])
Fulminant Liver Failure
Item
status 1 listing (fulminant hepatic failure) for liver transplant
boolean
C0162557 (UMLS CUI [1])
Substance Use Disorders
Item
active drug abuse or alcohol use within six months
boolean
C0038586 (UMLS CUI [1])
Urine pregnancy test positive
Item
positive urine pregnancy test (females)
boolean
C0430059 (UMLS CUI [1])
Malignant Neoplasms
Item
diagnosis of active malignancy
boolean
C0006826 (UMLS CUI [1])
Bariatric Surgery
Item
history of prior bariatric surgery
boolean
C1456587 (UMLS CUI [1])
Patient Information failed | Compliance behavior Lacking
Item
failure to attend the initial patient information sessions or history of noncompliance
boolean
C1955348 (UMLS CUI [1,1])
C0231175 (UMLS CUI [1,2])
C1321605 (UMLS CUI [2,1])
C0332268 (UMLS CUI [2,2])
Informed Consent failed | Informed Consent Comprehension Unable
Item
failure to give consent for the study or to understand the proposed consent
boolean
C0021430 (UMLS CUI [1,1])
C0231175 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C0162340 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
Health Insurance failed
Item
failure of patient's insurance company to approve surgical intervention so as to avoid extensive cost burden on the patient
boolean
C0021682 (UMLS CUI [1,1])
C0231175 (UMLS CUI [1,2])