Age
Item
patients will be included if they are aged 18 years or older,
boolean
C0001779 (UMLS CUI [1])
Non-Small Cell Lung Carcinoma Biopsy
Item
with biopsy proven nsclc,
boolean
C0007131 (UMLS CUI [1,1])
C0005558 (UMLS CUI [1,2])
TNM clinical staging Resectable Marginal
Item
clinically staged t3-t4 marginally resectable i.e. deemed at risk to achieve <r0 resection (such as invasion of critical mediastinal or hilar structures, nodal extra-capsular extension, chest wall, vertebral bodies, compromised bronchial stump margin, based on ct images of the chest).
boolean
C3258246 (UMLS CUI [1,1])
C1514888 (UMLS CUI [1,2])
C0205284 (UMLS CUI [1,3])
Disease Pathologic TNM stage
Item
patients also need to be pathologically staged n0-1 disease,
boolean
C0012634 (UMLS CUI [1,1])
C1319019 (UMLS CUI [1,2])
Stereotactic Body Radiation Therapy Clinical target volume | CT Planned
Item
with an sbrt ctv≤200cm3, based on planning ct images.
boolean
C3896609 (UMLS CUI [1,1])
C0454198 (UMLS CUI [1,2])
C0040405 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
ECOG performance status
Item
ecog status is required to be <2 within 4 weeks prior to registration and
boolean
C1520224 (UMLS CUI [1])
Patient Operable
Item
patients must be deemed medically operable by the surgical team.
boolean
C0030705 (UMLS CUI [1,1])
C0205188 (UMLS CUI [1,2])
Patient Inoperable
Item
patients will be excluded if they are deemed medically inoperable by the surgical team
boolean
C0030705 (UMLS CUI [1,1])
C0205187 (UMLS CUI [1,2])
Weight loss Percentage Timespan
Item
and have a weight loss of ≥10% within 3 months prior to pathological diagnosis.
boolean
C1262477 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
C0872291 (UMLS CUI [1,3])
Medical contraindication Therapeutic radiology procedure | Connective Tissue Diseases | Dependence on Artificial cardiac pacemaker | Prior radiation therapy Absent
Item
patients will also have no absolute contraindication to rt such as connective tissue disease, pacemaker-dependent patient with the pacemaker receiving higher than tolerance dose, had no had previous rt to the current region of the study, that would result in overlap of rt fields,
boolean
C1301624 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
C0009782 (UMLS CUI [2])
C0439857 (UMLS CUI [3,1])
C0030163 (UMLS CUI [3,2])
C0279134 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
Local Therapy Other Absent | Exception Disease Progression
Item
patients must have no plans to receive other local therapy while on study, except at disease progression,
boolean
C1517925 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C0242656 (UMLS CUI [2,2])
Cancer Other Absent | Exception Skin carcinoma
Item
patients have not had other malignancy within 2 years prior to the study (other than non-melanomatous skin cancers)
boolean
C1707251 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])