Nasopharyngeal carcinoma
Item
1.histological proven npc.
boolean
C2931822 (UMLS CUI [1])
TNM clinical staging
Item
2.2010 ajcc stage ii-ivb.
boolean
C3258246 (UMLS CUI [1])
Age
Item
3.age ≧ 20 years old.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
4.performance status of ecog ≦ 2.
boolean
C1520224 (UMLS CUI [1])
Therapeutic radiology procedure Completed | Induction Chemotherapy | Induction Chemotherapy Absent | Chemotherapy | Chemotherapy Absent
Item
5.finished rt ≧ 66 gy (± induction and/or concurrent chemotherapy).
boolean
C1522449 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C3179010 (UMLS CUI [2])
C3179010 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C0392920 (UMLS CUI [4])
C0392920 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
Epstein-Barr virus DNA Measurement | Status post Therapeutic radiology procedure
Item
6.pebv dna > 0 copy/ml at 1±1 week post-rt.
boolean
C0369169 (UMLS CUI [1,1])
C0242485 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C1522449 (UMLS CUI [2,2])
Lesion Absent | Status post Therapeutic radiology procedure
Item
7.re-staging work-ups at 10±2 weeks post-rt showing no active lesions.
boolean
C0221198 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C1522449 (UMLS CUI [2,2])
Liver function | Renal function | Bone Marrow function
Item
8.adequate liver, renal, and bone marrow function 4 weeks before randomization.
boolean
C0232741 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0005953 (UMLS CUI [3,1])
C0031843 (UMLS CUI [3,2])
Informed Consent
Item
9.signed informed consent.
boolean
C0021430 (UMLS CUI [1])
Disease Locoregional | Distant metastasis
Item
1. pathologically-proven the presence of locoregional disease and/or distant metastasis.
boolean
C0012634 (UMLS CUI [1,1])
C1947913 (UMLS CUI [1,2])
C1269798 (UMLS CUI [2])
Nasopharyngeal carcinoma Locoregional Imaging study | Nasopharyngeal carcinoma Distant Imaging study
Item
2. unequivocally-shown active npc (locoregional/distant) by imaging studies.
boolean
C2931822 (UMLS CUI [1,1])
C1947913 (UMLS CUI [1,2])
C1881134 (UMLS CUI [1,3])
C2931822 (UMLS CUI [2,1])
C0443203 (UMLS CUI [2,2])
C1881134 (UMLS CUI [2,3])
Therapeutic radiology procedure Inadequate
Item
3. inadequate rt.
boolean
C1522449 (UMLS CUI [1,1])
C0205412 (UMLS CUI [1,2])
Adjuvant Chemotherapy Post Therapeutic radiology procedure
Item
4. received any post-rt adjuvant chemotherapy.
boolean
C0085533 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C1522449 (UMLS CUI [1,3])
Epstein-Barr virus DNA Measurement | Status post Therapeutic radiology procedure
Item
5. pebv dna = 0 copy/ml at 1±1 week post-rt.
boolean
C0369169 (UMLS CUI [1,1])
C0242485 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C1522449 (UMLS CUI [2,2])
Cisplatin Dose
Item
6. previous delivery of cisplatin dose > 600 mg/m2.
boolean
C0008838 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
Epirubicin Dose
Item
7. previous delivery of epirubicin > 360 mg/m2.
boolean
C0014582 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
Malignant Neoplasms | Exception Curative treatment Skin carcinoma | Exception Curative treatment Carcinoma in situ of uterine cervix | Exception Curative treatment DCIS
Item
8. history of a malignancy except those treated with curative intent for skin cancer (other than melanoma), in situ cervical cancer, ductal carcinoma in situ (dcis) of breast.
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1273390 (UMLS CUI [2,2])
C0699893 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C1273390 (UMLS CUI [3,2])
C0851140 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C1273390 (UMLS CUI [4,2])
C0007124 (UMLS CUI [4,3])
Disease Cardiopulmonary Severe | Angina, Unstable | Congestive heart failure | Peripheral Vascular Disease Hospitalization Required | COPD exacerbation | Respiration Disorders Hospitalization Required | Mental disorders
Item
9. severe cardiopulmonary diseases (unstable angina and/or congestive heart failure or peripheral vascular disease requiring hospitalization within the last 12 months; chronic obstructive pulmonary disease exacerbation other respiratory illness requiring hospitalization) or clinically significant psychiatric disorders.
boolean
C0012634 (UMLS CUI [1,1])
C0553534 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C0002965 (UMLS CUI [2])
C0018802 (UMLS CUI [3])
C0085096 (UMLS CUI [4,1])
C1708385 (UMLS CUI [4,2])
C0740304 (UMLS CUI [5])
C0035204 (UMLS CUI [6,1])
C1708385 (UMLS CUI [6,2])
C0004936 (UMLS CUI [7])
Pregnancy | Breast Feeding
Item
10. female patients who are pregnant or lactating.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])