Multiple Sclerosis, Relapsing-Remitting
Item
definite relapsing-remitting ms according to the mcdonald criteria
boolean
C0751967 (UMLS CUI [1])
Interferon beta-1a | Avonex
Item
treated with ifnß-1a (avonex®) for at least 6 months
boolean
C0254119 (UMLS CUI [1])
C0594372 (UMLS CUI [2])
Influenza-like symptoms | Myalgia | Chills | Fatigue | Fever | Status post Interferon beta-1a Injection
Item
frequent experiencing fls (muscle aches, chills, fatigue, fewer9) in the hours following ifnß-1a injection (self-reporting that this happens 75% or more of the times after injection).
boolean
C0392171 (UMLS CUI [1])
C0231528 (UMLS CUI [2])
C0085593 (UMLS CUI [3])
C0015672 (UMLS CUI [4])
C0015967 (UMLS CUI [5])
C0231290 (UMLS CUI [6,1])
C4026102 (UMLS CUI [6,2])
Childbearing Potential Contraceptive methods
Item
female subjects of childbearing potential are required to practice effective contraception during the study and to continue contraception for 30 days after their last dose of study treatment.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Aerobic Exercise Completion
Item
expected to be able to complete the aerobic exercise intervention
boolean
C0001701 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
Patient Transport Self Exercise Facility
Item
willingly to transport themselves to the exercise/testing facility
boolean
C0150390 (UMLS CUI [1,1])
C0036588 (UMLS CUI [1,2])
C0015259 (UMLS CUI [1,3])
C1547538 (UMLS CUI [1,4])
Informed Consent
Item
give informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
age above 18 years
boolean
C0001779 (UMLS CUI [1])
Influenza-like symptoms Recent | Myalgia | Chills | Fatigue | Fever | Communicable Disease Serious Recent | Influenza-like symptoms chronic | Chronic infectious disease
Item
have fls (i.e. muscle aches, chills, fatigue or fewer) or serious infection within a 24h period prior to the screening. patients having chronic fls or infection will, therefore, be excluded. this will be tested by patient interview and, if required, further examination
boolean
C0392171 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
C0231528 (UMLS CUI [2])
C0085593 (UMLS CUI [3])
C0015672 (UMLS CUI [4])
C0015967 (UMLS CUI [5])
C0009450 (UMLS CUI [6,1])
C0205404 (UMLS CUI [6,2])
C0332185 (UMLS CUI [6,3])
C0392171 (UMLS CUI [7,1])
C0205191 (UMLS CUI [7,2])
C0151317 (UMLS CUI [8])
Hepatitis B | Hepatitis C | HIV Infection | Hepatitis B test positive | Hepatitis C test positive | HIV Seropositivity
Item
have a known history or positive test result for hepatitis b, hepatitis c, or hiv
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
C0019693 (UMLS CUI [3])
C1608966 (UMLS CUI [4])
C1609517 (UMLS CUI [5])
C0019699 (UMLS CUI [6])
Adrenergic beta-1 Receptor Antagonists
Item
use beta-blockers.
boolean
C0304516 (UMLS CUI [1])
Laboratory test result abnormal | ECG abnormal | Chronic Fatigue Syndrome | Fibromyalgia | Disease Premalignant | Malignant disease
Item
have clinically significant abnormality in laboratory or electrocardiogram measures, chronic fatigue syndrome or fibromyalgia, pre-malignant disease, or malignant disease
boolean
C0438215 (UMLS CUI [1])
C0522055 (UMLS CUI [2])
C0015674 (UMLS CUI [3])
C0016053 (UMLS CUI [4])
C0012634 (UMLS CUI [5,1])
C1514391 (UMLS CUI [5,2])
C0442867 (UMLS CUI [6])
Allergy Shot | Desensitization therapy | Vaccination
Item
have had allergy shot or desensitization therapy within 1 month of day 1 (randomization) vaccination within 2 weeks of day 1.
boolean
C1510857 (UMLS CUI [1])
C0178702 (UMLS CUI [2])
C0042196 (UMLS CUI [3])
Interferon beta-1a Discontinued
Item
stop taking ifnß-1a.
boolean
C0254119 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
Pregnancy
Item
are pregnant.
boolean
C0032961 (UMLS CUI [1])
Dementia | Alcohol abuse | Artificial cardiac pacemaker
Item
suffer from dementia, alcohol abuse or have a pacemaker.
boolean
C0497327 (UMLS CUI [1])
C0085762 (UMLS CUI [2])
C0030163 (UMLS CUI [3])