Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive
Item
patients with relapsing remitting multiple sclerosis (rrms), secondary progressive multiple sclerosis (spms) or primary progressive multiple sclerosis (ppms) fulfilling the mcdonald criteria
boolean
C0751967 (UMLS CUI [1])
C0751965 (UMLS CUI [2])
C0751964 (UMLS CUI [3])
EDSS
Item
expandend disability status scale (edss) 3-6.5
boolean
C0451246 (UMLS CUI [1])
KFSS - Pyramidal Functions
Item
pyramidal functional score ≥ 2
boolean
C3829393 (UMLS CUI [1])
Patient Transport Self
Item
participants must be able to transport self to gym and to the university of southern denmark
boolean
C0150390 (UMLS CUI [1,1])
C0036588 (UMLS CUI [1,2])
Timed 25-Foot Walk Functional Test Completion | Other Coding
Item
participants must be able to complete t25fw and ssst
boolean
C3897356 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C3846158 (UMLS CUI [2])
Childbearing Potential Hormonal contraception
Item
fertile female participants are obliged to use hormonal contraceptive measures
boolean
C3831118 (UMLS CUI [1,1])
C2985296 (UMLS CUI [1,2])
Epileptic Seizures
Item
history of epileptic seizures
boolean
C4317109 (UMLS CUI [1])
Multiple sclerosis relapse | Change in Disease Modification Therapy
Item
ms relapse or change in disease modifying treatment (dmt) within 60 days
boolean
C0856120 (UMLS CUI [1])
C0443172 (UMLS CUI [2,1])
C0012634 (UMLS CUI [2,2])
C3840684 (UMLS CUI [2,3])
C0087111 (UMLS CUI [2,4])
Malignant Neoplasms
Item
cancer within five years
boolean
C0006826 (UMLS CUI [1])
Blood pressure determination
Item
blood pressure ≥ 160/100
boolean
C0005824 (UMLS CUI [1])
Cardiac Arrhythmia Severe | Myocardial Ischemia | Heart Auscultation Abnormal Unexplained
Item
severe arrhythmia or ischaemic heart disease or unexplained abnormal cardiac auscultation
boolean
C0003811 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0151744 (UMLS CUI [2])
C0018793 (UMLS CUI [3,1])
C0205161 (UMLS CUI [3,2])
C4288071 (UMLS CUI [3,3])
Alanine aminotransferase measurement | Bromsulphtalein measurement | Gamma glutamyl transferase measurement
Item
≥ alt 90 u/l, ≥ bsp 210 u/l, ≥ γ-gt 230 u/l
boolean
C0201836 (UMLS CUI [1])
C0282359 (UMLS CUI [2,1])
C0242485 (UMLS CUI [2,2])
C0202035 (UMLS CUI [3])
Glomerular Filtration Rate
Item
gfr < 80 ml/min.
boolean
C0017654 (UMLS CUI [1])
Lung disease Severe | Auscultation pulmonary abnormal unexplained
Item
history of severe pulmonary disease or unexplained abnormal pulmonary auscultation
boolean
C0024115 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0004339 (UMLS CUI [2,1])
C0024109 (UMLS CUI [2,2])
C0205161 (UMLS CUI [2,3])
C4288071 (UMLS CUI [2,4])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
Breast Feeding
Item
breastfeeding
boolean
C0006147 (UMLS CUI [1])
Hypersensitivity Dalfampridine Prolonged-release
Item
allergy to substances contained in prolonged release fampridine tablets
boolean
C0020517 (UMLS CUI [1,1])
C0000477 (UMLS CUI [1,2])
C4544856 (UMLS CUI [1,3])
carvedilol | Propranolol | Metformin
Item
concomitant treatment with carvedilol, propranolol or metformin.
boolean
C0054836 (UMLS CUI [1])
C0033497 (UMLS CUI [2])
C0025598 (UMLS CUI [3])