Informed Consent
Item
patients willing to sign informed consent and capable of understanding the features of this clinical trial.
boolean
C0021430 (UMLS CUI [1])
Subject Diary Weekly | Observation Receive
Item
willing to keep a weekly diary and undergo observation for 12 months
boolean
C3890583 (UMLS CUI [1,1])
C0332174 (UMLS CUI [1,2])
C0302523 (UMLS CUI [2,1])
C1514756 (UMLS CUI [2,2])
Pregnancy Absent | Age | Multiple Sclerosis
Item
non-pregnant patients 18-55 years of age with ms according to the revised mcdonald criteria and meeting the poser criteria for clinically defined ms.
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
C0026769 (UMLS CUI [3])
EDSS | Status post Multiple Sclerosis Attack
Item
edss scores of 2·0 to 5·5 points assessed at least 3 months after the last acute attack of ms.
boolean
C0451246 (UMLS CUI [1])
C0231290 (UMLS CUI [2,1])
C0026769 (UMLS CUI [2,2])
C1304680 (UMLS CUI [2,3])
Health Insurance Country of residence
Item
must have proof of health insurance in country of residence.
boolean
C0021682 (UMLS CUI [1,1])
C1562954 (UMLS CUI [1,2])
Proliferative retinopathy
Item
patients with evidence of active proliferative retinopathy.
boolean
C0339467 (UMLS CUI [1])
Poorly controlled diabetes mellitus | Hemoglobin A1c measurement
Item
patients with poorly controlled diabetes mellitus (glycated hemoglobin: hba1c > 8.5%).
boolean
C0554876 (UMLS CUI [1])
C0474680 (UMLS CUI [2])
Renal Insufficiency | Creatinine measurement, serum | Kidney Failure
Item
patients with renal insufficiency (creatinine> 2.5) or failure.
boolean
C1565489 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
Communicable Disease | White Blood Cell Count procedure | Body temperature measurement
Item
infection as evidenced by white blood cell (wbc) count of >15,000 k/cumm and/or temperature > 38 celsius.
boolean
C0009450 (UMLS CUI [1])
C0023508 (UMLS CUI [2])
C0886414 (UMLS CUI [3])
Organ Transplantation
Item
history of organ transplant.
boolean
C0029216 (UMLS CUI [1])
Malignant Neoplasms | Exception Basal cell carcinoma Localized | Exception Squamous cell carcinoma of skin Localized | Exception Carcinoma in situ of uterine cervix
Item
history of previous or active malignancy, except for localised cutaneous basal or squamous cell carcinoma or carcinoma in situ of the cervix
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C0392752 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0553723 (UMLS CUI [3,2])
C0392752 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0851140 (UMLS CUI [4,2])
Angina Pectoris Limiting Exercise | Canadian Cardiovascular Society Grading Scale Class
Item
exercise limiting angina ( canadian cardiovascular society class 3
boolean
C0002962 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0015259 (UMLS CUI [1,3])
C1879987 (UMLS CUI [2])
Congestive heart failure New York Heart Association Classification
Item
congestive heart failure (new york heart association class 3
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Angina, Unstable
Item
unstable angina
boolean
C0002965 (UMLS CUI [1])
ST segment elevation myocardial infarction
Item
acute st elevation myocardial infarction (mi) within 1month
boolean
C1536220 (UMLS CUI [1])
Transient Ischemic Attack | Cerebrovascular accident
Item
transient ischemic heart attack or stroke within 1 month
boolean
C0007787 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
Heart valve disease Severe
Item
severe valvular heart disease
boolean
C0018824 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])