Age
Item
Is the patient 18 years old or older?
boolean
C0001779 (UMLS CUI [1])
Colorectal carcinoma
Item
Does the participant have a carcinoma of the colon and/or rectum?
boolean
C0009402 (UMLS CUI [1])
Disease Progression
Item
Does the patient have disease progression during or within 6 months of last dose of oxaliplatin containing first-line combination therapy for metastatic disease?
boolean
C0242656 (UMLS CUI [1,1])
C0069717 (UMLS CUI [1,2])
ECOG Performance Status
Item
Does the participant have an ecog performance status of 0-1?
boolean
C1520224 (UMLS CUI [1])
Hematological, Renal and Liver Function
Item
Does the participant have adequate hematological, renal and liver function?
boolean
C0221130 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
Prior anti-EGFR treatment
Item
Did the participant have prior treatment with monoclonal antibody/small molecule against epidermal growth factor receptor (egfr)?
boolean
C1443775 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
C4055105 (UMLS CUI [1,3])
Prior irinotecan treatment
Item
Did the participant have prior treatment with irinotecan?
boolean
C1514463 (UMLS CUI [1,1])
C0123931 (UMLS CUI [1,2])
Prior Radiotherapy
Item
Did the participant have radiotherapy within the last 4 weeks before first dose of study drug (except for limited field palliative radiotherapy for bone pain relief)?
boolean
C0279134 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
CNS metastasis
Item
Does the participant have a CNS metastasis?
boolean
C0686377 (UMLS CUI [1])
Autoimmune disorders
Item
Does the participant have a history of or an active autoimmune disorder(s)/condition(s)?
boolean
C0262926 (UMLS CUI [1,1])
C0004364 (UMLS CUI [1,2])
C0205177 (UMLS CUI [2,1])
C0004364 (UMLS CUI [2,2])