Gender
Item
1. male, or female
boolean
C0079399 (UMLS CUI [1])
Age
Item
2. between the ages of 18-50.
boolean
C0001779 (UMLS CUI [1])
General health good
Item
3. in good general health
boolean
C1277245 (UMLS CUI [1])
Mental disorders | Dysthymic Disorder | Phobia Simple | Major Depressive Disorder | Obsessive-Compulsive Disorder | Panic Disorder
Item
1. subjects who report a history of any mental health disorder such as dysthymia, simple phobia, major depression, obsessive compulsive disorder or panic disorder as a primary diagnosis currently or within 6 months prior to the screening visit.
boolean
C0004936 (UMLS CUI [1])
C0013415 (UMLS CUI [2])
C0236801 (UMLS CUI [3])
C1269683 (UMLS CUI [4])
C0028768 (UMLS CUI [5])
C0030319 (UMLS CUI [6])
Schizophrenia | Schizoaffective Disorder | Bipolar Disorder
Item
2. subjects with a history of schizophrenia, schizoaffective disorder, or a bipolar disorder.
boolean
C0036341 (UMLS CUI [1])
C0036337 (UMLS CUI [2])
C0005586 (UMLS CUI [3])
Substance Use Disorders
Item
3. subjects who report dsm-v criteria for substance use disorder (alcohol or drugs) currently or within 6 months prior to screening
boolean
C0038586 (UMLS CUI [1])
Urine drug screen positive Illicit Drug
Item
4. subjects who have a positive urine illicit drug screen.
boolean
C0743300 (UMLS CUI [1,1])
C0086190 (UMLS CUI [1,2])
NSAIDs Regular
Item
5. subjects that regularly (more than 15 days for past 30 days) use nsaids and have not used nsaids in the previous 5 days.
boolean
C0003211 (UMLS CUI [1,1])
C0205272 (UMLS CUI [1,2])
Liver diseases | Heart Diseases | Kidney Diseases | Nervous system disorder | Cerebrovascular Disorders | Metabolic Diseases | Lung diseases | Stomach Diseases
Item
6. subjects with a history of clinically significant hepatic cardiac, renal, neurologic, cerebrovascular, metabolic or pulmonary disease, gastric disease.
boolean
C0023895 (UMLS CUI [1])
C0018799 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C0027765 (UMLS CUI [4])
C0007820 (UMLS CUI [5])
C0025517 (UMLS CUI [6])
C0024115 (UMLS CUI [7])
C0038354 (UMLS CUI [8])
Psychotropic Drugs | Antidepressive Agents | Monoamine Oxidase Inhibitors
Item
7. subjects who have taken psychotropic drugs or antidepressants (including monoamine oxidase inhibitors, maoi's) within the last year
boolean
C0033978 (UMLS CUI [1])
C0003289 (UMLS CUI [2])
C0026457 (UMLS CUI [3])
Seizure disorders | Exception Febrile seizures in early childhood
Item
8. subjects with a history of seizure disorders (except for febrile seizures in childhood).
boolean
C0014544 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0009952 (UMLS CUI [2,2])
At risk for suicide serious | Risk homicidal serious | Suicide attempt
Item
9. subjects who, in the investigator's judgment pose a current, serious suicidal or homicidal risk or have made a suicide attempt within the past 6 months.
boolean
C0563664 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0035647 (UMLS CUI [2,1])
C0745031 (UMLS CUI [2,2])
C0205404 (UMLS CUI [2,3])
C0038663 (UMLS CUI [3])
Serum pregnancy test (B-HCG) Positive | Breast Feeding | Pregnancy, Planned
Item
10. women who have a positive serum hcg pregnancy test at screen visit or who are lactating or planning to become pregnant within the next 18 weeks following the screen visit.
boolean
C0430060 (UMLS CUI [1,1])
C1446409 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Gender Menstruation
Item
11. women who are currently menstruating.
boolean
C0079399 (UMLS CUI [1,1])
C0025344 (UMLS CUI [1,2])
Claustrophobia | Phobia Injection | Fear of blood
Item
12. the subject suffers from claustrophobia, or phobia for injections or blood.
boolean
C0008909 (UMLS CUI [1])
C0349231 (UMLS CUI [2,1])
C1533685 (UMLS CUI [2,2])
C0522183 (UMLS CUI [3])
Magnetic Resonance Imaging Exclusion Criteria | Artificial cardiac pacemaker | Metal foreign body in eye region | Metal splinters in skin | Metallic foreign body Human body | Shrapnel Human body | Metal worker | Welder | Ophthalmologic Surgical Procedures | Eye Washout Due to Metal | Clip Aortic | Aneurysm clip | Prosthesis | Bypass surgery Clip | Coronary artery clip | Hearing Aid | Prosthetic replacement of heart valve | Pregnancy Trimester, First | Intrauterine Device | Shunt Ventricular | Shunt spinal | Electrode | Metal plates | Pins metallic | Screw | Wire | Neurostimulator | Tens unit electrodes
Item
13. magnetic resonance imaging related exclusion criteria: cardiac pacemaker, metal fragments in eyes/skin/body (shrapnel), subjects who have ever been a metal worker/welder; history of eye surgery/eyes washed out because of metal, aortic/aneurysm clips, prosthesis, by-pass surgery/coronary artery clips, hearing aid, heart valve replacement, subjects who are in the first trimester of pregnancy, subjects with an i.u.d. (birth control device), a shunt (ventricular or spinal), electrodes, metal plates/pins/screws/wires, or neuro/bio-stimulators (tens unit).
boolean
C0024485 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0030163 (UMLS CUI [2])
C0562528 (UMLS CUI [3])
C2229035 (UMLS CUI [4])
C1720389 (UMLS CUI [5,1])
C1318419 (UMLS CUI [5,2])
C0522670 (UMLS CUI [6,1])
C1318419 (UMLS CUI [6,2])
C0402937 (UMLS CUI [7])
C0336106 (UMLS CUI [8])
C0038901 (UMLS CUI [9])
C0015392 (UMLS CUI [10,1])
C1710661 (UMLS CUI [10,2])
C0678226 (UMLS CUI [10,3])
C0025552 (UMLS CUI [10,4])
C0175722 (UMLS CUI [11,1])
C0003483 (UMLS CUI [11,2])
C0179977 (UMLS CUI [12])
C0175649 (UMLS CUI [13])
C1536078 (UMLS CUI [14,1])
C0175722 (UMLS CUI [14,2])
C4510021 (UMLS CUI [15])
C0018768 (UMLS CUI [16])
C0190163 (UMLS CUI [17])
C0032979 (UMLS CUI [18])
C0021900 (UMLS CUI [19])
C0542331 (UMLS CUI [20,1])
C0018827 (UMLS CUI [20,2])
C0542331 (UMLS CUI [21,1])
C0521329 (UMLS CUI [21,2])
C0013812 (UMLS CUI [22])
C0013866 (UMLS CUI [23])
C0175718 (UMLS CUI [24,1])
C2986473 (UMLS CUI [24,2])
C0301559 (UMLS CUI [25])
C4522306 (UMLS CUI [26])
C0582124 (UMLS CUI [27])
C1967354 (UMLS CUI [28])