DEPRESSIVE DISORDER MAJOR WITHOUT PSYCHOTIC FEATURE Unipolar | Major depressive episode Duration
Item
1. current dsm-iv diagnosis of mdd, unipolar type, without psychotic features and 6 weeks minimum duration of current depressive episode.
boolean
C0743081 (UMLS CUI [1,1])
C0443340 (UMLS CUI [1,2])
C0024517 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
Moderate major depression Hamilton depression rating scale (HDRS)
Item
2. moderate severity of depression using the hamilton depression rating scale (hdrs > 20).
boolean
C0270456 (UMLS CUI [1,1])
C2021166 (UMLS CUI [1,2])
Able to speak English Language
Item
3. english speaking, male or female
boolean
C0564215 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
Age
Item
4. 65 years of age or older
boolean
C0001779 (UMLS CUI [1])
General health good
Item
5. good general health
boolean
C1277245 (UMLS CUI [1])
Informed Consent
Item
6. able to give informed consent
boolean
C0021430 (UMLS CUI [1])
Antidepressive Agents | Psychotherapy | Electroconvulsive Therapy
Item
1. antidepressant use or psychotherapy within the past 6 weeks or electroconvulsive therapy within the past 6 months.
boolean
C0003289 (UMLS CUI [1])
C0033968 (UMLS CUI [2])
C0013806 (UMLS CUI [3])
Substance Use Disorders | Substance Dependence
Item
2. recent history (<6 months) of substance or alcohol abuse or dependence (dsm-iv criteria).
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
Nootropic Agents
Item
3. use of cognitive enhancing medications.
boolean
C0242913 (UMLS CUI [1])
Post-Traumatic Stress Disorder | Axis I diagnosis
Item
4. current diagnosis of post-traumatic stress disorder or other axis 1 psychiatric disorder.
boolean
C0038436 (UMLS CUI [1])
C0270287 (UMLS CUI [2])
Nervous system disorder | Parkinson Disease | Epilepsy | Stroke cortical | Alzheimer's Disease | Traumatic Brain Injury | Dementia
Item
5. neurological diseases (e.g., parkinson's disease, epilepsy, cortical stroke, alzheimer's disease, traumatic brain injury) or dementia.
boolean
C0027765 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C0038454 (UMLS CUI [4,1])
C0007776 (UMLS CUI [4,2])
C0002395 (UMLS CUI [5])
C0876926 (UMLS CUI [6])
C0497327 (UMLS CUI [7])
Operative Surgical Procedures Affecting Research results
Item
6. history of surgical procedures affecting study outcomes.
boolean
C0543467 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0683954 (UMLS CUI [1,3])
Medical contraindication MRI | Claustrophobia | Metallic implant | Patients Appropriate MRI Machine | Body mass index
Item
7. contraindications for mr exam, i.e., no claustrophobia, no paramagnetic metal implants, able to fit in the mri machine comfortably (bmi ≤ 38).
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0008909 (UMLS CUI [2])
C3693688 (UMLS CUI [3])
C0030705 (UMLS CUI [4,1])
C1548787 (UMLS CUI [4,2])
C0024485 (UMLS CUI [4,3])
C0336779 (UMLS CUI [4,4])
C1305855 (UMLS CUI [5])
Acute illness | Illness Uncontrolled Impact Cognitive function
Item
8. acute or uncontrolled medical illness or medication use impacting cognitive function.
boolean
C4061114 (UMLS CUI [1])
C0221423 (UMLS CUI [2])
C0205318 (UMLS CUI [3,1])
C4049986 (UMLS CUI [3,2])
C0392335 (UMLS CUI [3,3])