Postmenopausal state
Item
postmenopausal women
boolean
C0232970 (UMLS CUI [1])
Postmenopausal state | Amenorrhea Duration | Hysterectomy | Outpatients | Inpatient | Locally advanced breast cancer | Secondary malignant neoplasm of female breast | Prior antiestrogen therapy failed
Item
postmenopausal: amenorrhea over 12 months prior to the visit 1 or history of hysterectomy 2) outpatient or inpatient with locally advanced or metastatic breast cancer who have failed with prior anti-estrogen therapy.
boolean
C0232970 (UMLS CUI [1])
C0002453 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
C0020699 (UMLS CUI [3])
C0029921 (UMLS CUI [4])
C0021562 (UMLS CUI [5])
C3495949 (UMLS CUI [6])
C0346993 (UMLS CUI [7])
C0279797 (UMLS CUI [8,1])
C0231175 (UMLS CUI [8,2])
Patients Estrogen receptor positive | Disease Progression Radiography | Status post Prior Therapy | Informed Consent
Item
estrogen receptor positive 4)radiographic progression of disease after the prior therapy 5) patients who agree to participate in this study and sign the informed consent
boolean
C0030705 (UMLS CUI [1,1])
C0279754 (UMLS CUI [1,2])
C0242656 (UMLS CUI [2,1])
C0034571 (UMLS CUI [2,2])
C0231290 (UMLS CUI [3,1])
C1514463 (UMLS CUI [3,2])
C0021430 (UMLS CUI [4])
fulvestrant
Item
patients who are treated with fulvestrant
boolean
C0935916 (UMLS CUI [1])
Antineoplastic Agents
Item
patients who are being treated with the other antitumor agents
boolean
C0003392 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnancy or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hypersensitivity Ingredient | Castor oil allergy | Patients Medically unfit
Item
history of hypersensitivity to any of included ingredients (eg. castor oil) 5) patients who are considered not fit for the study by investigators
boolean
C0020517 (UMLS CUI [1,1])
C1550600 (UMLS CUI [1,2])
C0571232 (UMLS CUI [2])
C0030705 (UMLS CUI [3,1])
C3841806 (UMLS CUI [3,2])
Liver Dysfunction Severe | Renal dysfunction Severe
Item
patients who have severe dysfunction of liver or kidney
boolean
C0086565 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C3279454 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Elevated total bilirubin
Item
total bilirubin > 5 x uln
boolean
C0741494 (UMLS CUI [1])
Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
ast/alt > 5 x uln
boolean
C0151904 (UMLS CUI [1])
C0151905 (UMLS CUI [2])
Creatinine increased
Item
creatinine > 2 x uln
boolean
C0151578 (UMLS CUI [1])