Knee Osteoarthritis Mild | Knee Osteoarthritis Moderate | Other Coding | Osteophytes Diagnostic radiologic examination | Narrowed joint space Diagnostic radiologic examination
Item
physician-diagnosed mild to moderate knee osteoarthritis (oarsi atlas grades 1-2) based on fixed-flexion x-ray radiological findings for osteophytes and joint space narrowing within the past 12 months
boolean
C0409959 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C0409959 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C3846158 (UMLS CUI [3])
C1956089 (UMLS CUI [4,1])
C0043299 (UMLS CUI [4,2])
C1859695 (UMLS CUI [5,1])
C0043299 (UMLS CUI [5,2])
Osteoarthritis, Knee
Item
fulfill the american college of rheumatology clinical and radiological diagnostic criteria for knee oa
boolean
C0409959 (UMLS CUI [1])
Age
Item
35-80 years of age
boolean
C0001779 (UMLS CUI [1])
Visual Analog Pain Scale
Item
report a frequent pain score between 3-7 (vas range: 0-10) during the week preceding enrollment
boolean
C0042815 (UMLS CUI [1])
Knee pain Limiting Quality of life
Item
report that knee pain negatively affects quality of life
boolean
C0231749 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0034380 (UMLS CUI [1,3])
Use of Ultrasound gel Approved
Item
willing not to use any cream, gel, or topical solution during the administration of treatment other than the approved ultrasound gel provided to the subject at the initiation of the study
boolean
C1524063 (UMLS CUI [1,1])
C0361557 (UMLS CUI [1,2])
C0205540 (UMLS CUI [1,3])
Study Subject Participation Status Appropriate
Item
deemed appropriate by their physician or by the study site physician to participate
boolean
C2348568 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
Use of Medical Device Unable
Item
cannot successfully demonstrate the ability to put on and take off the device
boolean
C1524063 (UMLS CUI [1,1])
C0025080 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Condition Study Subject Participation Status Unacceptable | Comprehension Instructions Unable | Adherence Instructions Unable
Item
display any condition which, in the judgment of the investigator, would make participation in the study unacceptable, including, but not limited to, the subject's ability to understand and follow instructions.
boolean
C0348080 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1883420 (UMLS CUI [1,3])
C0162340 (UMLS CUI [2,1])
C2051542 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
C1510802 (UMLS CUI [3,1])
C2051542 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])
Osteoarthritis Severe | Articular cartilage of knee joint Little | Articular cartilage of knee joint Lacking
Item
have severe oa or have little to no cartilage in the knee
boolean
C0029408 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0582925 (UMLS CUI [2,1])
C0700321 (UMLS CUI [2,2])
C0582925 (UMLS CUI [3,1])
C0332268 (UMLS CUI [3,2])
Knee Replacement | Surgical intervention | Hyaluronidase injection Knee affected
Item
have knee replacement, other surgical intervention, or hyaluronidase injection in the affected knee in the past 6 months
boolean
C0086511 (UMLS CUI [1])
C0549433 (UMLS CUI [2])
C4283365 (UMLS CUI [3,1])
C0022742 (UMLS CUI [3,2])
C1314939 (UMLS CUI [3,3])
Non-ambulatory
Item
are non-ambulatory
boolean
C0560046 (UMLS CUI [1])
Study Subject Participation Status | Investigational New Drugs
Item
participated in a clinical trial for an investigational drug and/or agent within 30 days prior to screening
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Modification Pharmaceutical Preparations
Item
modify their medications during the course of the study (medications and doses must remain constant throughout the study)
boolean
C3840684 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
Taking steroids
Item
currently taking steroids
boolean
C2054177 (UMLS CUI [1])
Medical contraindication Radiography
Item
have contraindication to radiograph
boolean
C1301624 (UMLS CUI [1,1])
C0034571 (UMLS CUI [1,2])
Cause Secondary Arthritis
Item
have a secondary cause of arthritis (metabolic or inflammatory)
boolean
C0015127 (UMLS CUI [1,1])
C0175668 (UMLS CUI [1,2])
C0003864 (UMLS CUI [1,3])