Childbearing Potential Absent | Male infertility
Item
male or female of non-child bearing potential
boolean
C3831118 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0021364 (UMLS CUI [2])
Good health | Exception Hepatitis C Genotype
Item
in good health other than hcv genotype (gt) 1 infection
boolean
C3813622 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0019196 (UMLS CUI [2,2])
C1285573 (UMLS CUI [2,3])
Mental handicap | Institutionalized Persons
Item
is mentally incapacitated or legally institutionalized
boolean
C1306341 (UMLS CUI [1])
C0376326 (UMLS CUI [2])
Endocrine System Diseases Poorly controlled | Gastrointestinal Diseases Poorly controlled | Cardiovascular Diseases Poorly controlled | Hematological Disease Poorly controlled | Liver diseases Poorly controlled | Exception Hepatitis C | Immune System Diseases Poorly controlled | Kidney Diseases Poorly controlled | Respiration Disorders Poorly controlled | Disorder of the genitourinary system Poorly controlled | Nervous system disorder Major Poorly controlled | Cerebrovascular accident Poorly controlled | Seizures chronic Poorly controlled
Item
has a history of clinically significant and not stably controlled endocrine, gastrointestinal, cardiovascular, hematological, hepatic (excepting hcv infection), immunological, renal, respiratory, genitourinary or major neurological (including stroke and chronic seizures) abnormalities or diseases
boolean
C0014130 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
C0017178 (UMLS CUI [2,1])
C3853134 (UMLS CUI [2,2])
C0007222 (UMLS CUI [3,1])
C3853134 (UMLS CUI [3,2])
C0018939 (UMLS CUI [4,1])
C3853134 (UMLS CUI [4,2])
C0023895 (UMLS CUI [5,1])
C3853134 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C0019196 (UMLS CUI [6,2])
C0021053 (UMLS CUI [7,1])
C3853134 (UMLS CUI [7,2])
C0022658 (UMLS CUI [8,1])
C3853134 (UMLS CUI [8,2])
C0035204 (UMLS CUI [9,1])
C3853134 (UMLS CUI [9,2])
C0080276 (UMLS CUI [10,1])
C3853134 (UMLS CUI [10,2])
C0027765 (UMLS CUI [11,1])
C0205164 (UMLS CUI [11,2])
C3853134 (UMLS CUI [11,3])
C0038454 (UMLS CUI [12,1])
C3853134 (UMLS CUI [12,2])
C0036572 (UMLS CUI [13,1])
C0205191 (UMLS CUI [13,2])
C3853134 (UMLS CUI [13,3])
Malignant Neoplasms
Item
has a history of cancer
boolean
C0006826 (UMLS CUI [1])
Hepatitis B surface antigen positive | HIV Seropositivity
Item
is positive for hepatitis b surface antigen (hbsag) or human immunodeficiency virus (hiv)
boolean
C0149709 (UMLS CUI [1])
C0019699 (UMLS CUI [2])
Study Subject Participation Status | Research study
Item
has participated in another investigational trial within 4 weeks (or 5 half-lives) prior to screening
boolean
C2348568 (UMLS CUI [1])
C0681814 (UMLS CUI [2])
Alcohol consumption Drinks U/day | Illicit medication use
Item
consumes >2 alcoholic beverages a day or uses illegal drugs
boolean
C0001948 (UMLS CUI [1,1])
C0001967 (UMLS CUI [1,2])
C0456683 (UMLS CUI [1,3])
C0281875 (UMLS CUI [2])
Hepatitis, Chronic | Etiology Absent HCV | Viral hepatitis | Nonalcoholic Steatohepatitis | Hepatitis, Drug-Induced | Hepatitis, Autoimmune
Item
has evidence or history of chronic hepatitis not caused by hcv including but not limited to non-hcv viral hepatitis, non-alcoholic steatohepatitis (nash), drug-induced hepatitis, or autoimmune hepatitis
boolean
C0019189 (UMLS CUI [1])
C0015127 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0220847 (UMLS CUI [2,3])
C0042721 (UMLS CUI [3])
C3241937 (UMLS CUI [4])
C1262760 (UMLS CUI [5])
C0241910 (UMLS CUI [6])
Liver disease Advanced | Decompensated liver disease | Bridging fibrosis | Fibrosis Severe Metavir score Biopsy of liver
Item
has clinical or laboratory evidence of advanced or decompensated liver disease, evidence of bridging fibrosis or higher grade fibrosis (metavir score ≥3) from prior liver biopsy
boolean
C0023895 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C4075847 (UMLS CUI [2])
C0334160 (UMLS CUI [3])
C0016059 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C3888527 (UMLS CUI [4,3])
C0193388 (UMLS CUI [4,4])