Cirrhosis with portal hypertension
Item
Cirrhosis with clinical and/or endoscopic evidence of portal hypertension (e.g. oesophageal varices)
boolean
C0023890 (UMLS CUI [1])
C0020541 (UMLS CUI [2])
Malfunctioning TIPSS
Item
Cirrhosis with TIPSS in situ and a portal pressure gradient >5mmHg
boolean
C0339897 (UMLS CUI [1,1])
C0086138 (UMLS CUI [1,2])
C0020541 (UMLS CUI [2])
C0023890 (UMLS CUI [3])
Fully functioning TIPSS
Item
Fully functioning TIPSS without variceal filling as confirmed by portography
boolean
C0339897 (UMLS CUI [1,1])
C0032723 (UMLS CUI [1,2])
C0542341 (UMLS CUI [1,3])
Alcoholic liver cirrhosis
Item
Cirrhosis of alcohol aetiology according to physician's assessment prior to screening
boolean
C0023891 (UMLS CUI [1])
BMI
Item
BMI > 40 kg/m2.
boolean
C1305855 (UMLS CUI [1])
MRI-Scan
Item
Any contraindication to having an MRI scan
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
Catheterization
Item
Contraindication to liver catheterization
boolean
C0007430 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C1301624 (UMLS CUI [1,3])
Drugs
Item
Use of any drug to treat portal hypertension (e.g. vasodilators such as non-selective beta blockers or nitrates) within 1 month prior to screening.
boolean
C0020541 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C0332185 (UMLS CUI [1,3])
C0087111 (UMLS CUI [1,4])
State of cirrhosis
Item
Decompensated cirrhosis (child-pugh score >9 points, and/or ascites requiring diuretics, and/or hepatic encephalopathy) at first visit
boolean
C1619727 (UMLS CUI [1])
C2347612 (UMLS CUI [2])
C0019151 (UMLS CUI [3])
C0003962 (UMLS CUI [4,1])
C0012798 (UMLS CUI [4,2])
C1514873 (UMLS CUI [4,3])
Non-controlled comorbidities
Item
Presence of any non-controlled and clinically significant disease that could affect the study outcome or that would place the patient at undue risk.
boolean
C0009488 (UMLS CUI [1,1])
C0035647 (UMLS CUI [1,2])
C0009488 (UMLS CUI [2,1])
C0543472 (UMLS CUI [2,2])
C0392760 (UMLS CUI [2,3])