Age
Item
male or female, above 18 years of age
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension
Item
diagnosis of essential hypertension
boolean
C0085580 (UMLS CUI [1])
Newly Diagnosed
Item
newly diagnosed,
boolean
C1518321 (UMLS CUI [1])
Untreated | Antihypertensive therapy Regular Lacking
Item
previously untreated, or currently untreated (not on regular antihypertensive treatment during the previous at least 1-month period)
boolean
C0332155 (UMLS CUI [1])
C0585941 (UMLS CUI [2,1])
C0205272 (UMLS CUI [2,2])
C0332268 (UMLS CUI [2,3])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Secondary hypertension | Secondary hypertension Suspected
Item
known or suspected secondary hypertension
boolean
C0155616 (UMLS CUI [1])
C0155616 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Estimated Glomerular Filtration Rate
Item
egfr lower than 30 ml/min
boolean
C3811844 (UMLS CUI [1])
Hypertension treatment Other | Patient need for Hypertension treatment
Item
use of any other hypertension treatments during the enrollment and need for using the related treatments during the study phase
boolean
C0578998 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0686904 (UMLS CUI [2,1])
C0578998 (UMLS CUI [2,2])
Hypersensitivity Investigational New Drugs | Hypersensitivity Pharmaceutical Preparations Similar | Hypersensitivity Valsartan | Amlodipine allergy | Hydrochlorothiazide allergy
Item
history of hypersensitivity to any of the study drugs or to drugs of similar chemical classes. (i.e. valsartan, amlodipine, hydrochlorothiazide)
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C2348205 (UMLS CUI [2,3])
C0020517 (UMLS CUI [3,1])
C0216784 (UMLS CUI [3,2])
C0570921 (UMLS CUI [4])
C0571898 (UMLS CUI [5])
Malignant Neoplasms Organ system | Exception Basal cell carcinoma Localized Treated | Exception Basal cell carcinoma Localized Untreated | Independent of Local Neoplasm Recurrence | Independent of Neoplasm Metastasis Local
Item
history of malignancy of any organ system (other than localized basal cell carcinoma of the skin), treated or untreated, within the past 5 years, regardless of whether there is evidence of local recurrence or metastases.
boolean
C0006826 (UMLS CUI [1,1])
C0460002 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C0392752 (UMLS CUI [2,3])
C1522326 (UMLS CUI [2,4])
C1705847 (UMLS CUI [3,1])
C0007117 (UMLS CUI [3,2])
C0392752 (UMLS CUI [3,3])
C0332155 (UMLS CUI [3,4])
C0332291 (UMLS CUI [4,1])
C0027643 (UMLS CUI [4,2])
C0332291 (UMLS CUI [5,1])
C0027627 (UMLS CUI [5,2])
C0205276 (UMLS CUI [5,3])
Investigational New Drugs | Pregnancy | Breast Feeding
Item
use of other investigational drugs within 5 half-lives of enrollment, or within 30 days until the expected pd effect has returned to baseline, whichever is longer.pregnant or nursing (lactating) women
boolean
C0013230 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
Eligibility Criteria Study Protocol
Item
other protocol-defined inclusion/exclusion criteria may apply.
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])