Breast Carcinoma | Breast-Conserving Surgery | Negative Surgical Margin | Independent of Risk factors Additional | Lymph node Status Positive | Lymph node Status Negative High risk | Estrogen Receptor Status | Progesterone Receptor Status | HER2/Neu Status | Urokinase Plasminogen Activator Inhibitor 1 Criteria | Systemic therapy Postoperative | Chemotherapy | Hormone Therapy | Antibody therapy | Diphosphonates
Item
histopathologically confirmed breast cancer operated by breast conserving surgery with clear margins independently of further risk factors (positive or high-risk negative lymph node status, estrogen- or progesterone receptor status, her-2/neu status upa/pai-1 criteria) and postoperative systemic therapy (chemotherapy, endocrine, antibody or bisphosphonate therapy were permitted when indicated)
boolean
C0678222 (UMLS CUI [1])
C0917927 (UMLS CUI [2])
C1709157 (UMLS CUI [3])
C0332291 (UMLS CUI [4,1])
C0035648 (UMLS CUI [4,2])
C1524062 (UMLS CUI [4,3])
C0024204 (UMLS CUI [5,1])
C0449438 (UMLS CUI [5,2])
C1514241 (UMLS CUI [5,3])
C0024204 (UMLS CUI [6,1])
C0449438 (UMLS CUI [6,2])
C1513916 (UMLS CUI [6,3])
C4319571 (UMLS CUI [6,4])
C0034804 (UMLS CUI [7,1])
C0449438 (UMLS CUI [7,2])
C1514471 (UMLS CUI [8])
C1512413 (UMLS CUI [9])
C0042071 (UMLS CUI [10,1])
C0030190 (UMLS CUI [10,2])
C0243161 (UMLS CUI [10,3])
C1515119 (UMLS CUI [11,1])
C0032790 (UMLS CUI [11,2])
C0392920 (UMLS CUI [12])
C0279025 (UMLS CUI [13])
C0281176 (UMLS CUI [14])
C0012544 (UMLS CUI [15])
Indication Adjuvant Radiotherapy | Indication Boost radiation therapy
Item
indication to adjuvant radiotherapy including boost radiotherapy
boolean
C3146298 (UMLS CUI [1,1])
C0242939 (UMLS CUI [1,2])
C3146298 (UMLS CUI [2,1])
C2919491 (UMLS CUI [2,2])
Primary tumor region Identified | Markers, Radiopaque
Item
clearly identified primary tumor region preferably by radiopaque clips
boolean
C0677930 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C0205396 (UMLS CUI [1,3])
C0181739 (UMLS CUI [2])
Wound Healing Post Breast conserving therapy | Signs Absent Communicable Disease
Item
primary wound healing after breast conserving therapy without signs of infection
boolean
C0043240 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C0024885 (UMLS CUI [1,3])
C0311392 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0009450 (UMLS CUI [2,3])
Age
Item
age ≥ 18 years
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
ecog ≤ 2 performance status
boolean
C1520224 (UMLS CUI [1])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Protocol Compliance
Item
compliance regarding treatment appointments and toxicity
boolean
C0525058 (UMLS CUI [1])
Language comprehension Questionnaires | Comprehension Questionnaires
Item
linguistic and cognitive ability to understand the questionnaires
boolean
C0233733 (UMLS CUI [1,1])
C0034394 (UMLS CUI [1,2])
C0162340 (UMLS CUI [2,1])
C0034394 (UMLS CUI [2,2])
Mastectomy
Item
patients operated by mastectomy
boolean
C0024881 (UMLS CUI [1])
Indication Boost radiation therapy | Status post Intraoperative radiation therapy
Item
no indication for boost radiation (e.g. status after iort)
boolean
C3146298 (UMLS CUI [1,1])
C2919491 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C0338240 (UMLS CUI [2,2])
Bilateral breast cancer
Item
double sided breast cancer
boolean
C0281267 (UMLS CUI [1])
Surgical margins Positive Disease | Boost Volume Identification Insufficient
Item
resection margins positive for disease or insufficient identification of the boost volume
boolean
C0229985 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
C0012634 (UMLS CUI [1,3])
C2919491 (UMLS CUI [2,1])
C0449468 (UMLS CUI [2,2])
C0205396 (UMLS CUI [2,3])
C0231180 (UMLS CUI [2,4])
Indication Therapeutic radiology procedure Regional lymph nodes
Item
indication for radiotherapy of the regional lymph nodes
boolean
C3146298 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
C1179441 (UMLS CUI [1,3])
Radiotherapy to breast Previous | Radiotherapy to thorax Previous
Item
history of prior breast or thoracic radiotherapy
boolean
C0948310 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C4038705 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
Postoperative seroma Extended
Item
extended postoperative seroma at the beginning of radiotherapy
boolean
C1998103 (UMLS CUI [1,1])
C0231449 (UMLS CUI [1,2])
Therapeutic radiology procedure Previous | Dose Required Lacking
Item
previously administered radiotherapy not allowing the required dose
boolean
C1522449 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0178602 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0332268 (UMLS CUI [2,3])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Lacking
Item
pregnant or lactating patients and woman of child bearing potential, who lacked effective contraception
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332268 (UMLS CUI [3,3])
Treatment Cancer Other | Study Subject Participation Status | Testing Therapeutic radiology procedure | Investigational New Drugs
Item
treatment history of other cancer or participation in another clinical trial testing radiotherapy or drugs within 4 weeks of the start of treatment.
boolean
C0087111 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])
C0039593 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
C0013230 (UMLS CUI [4])
Disease Adverse effects Treatment Compliance | Physical illness Serious Uncontrolled | Cerebrovascular Disorders Serious Uncontrolled | Myocardial Infarction | Nervous system disorder | Mental disorders
Item
patients with serious, uncontrolled, physical or cerebrovascular disorders(e.g. myocardial infarction within the last 12 months) or neurologiy or psychiatric disorders thought to adversly affect treatment compliance
boolean
C0012634 (UMLS CUI [1,1])
C0879626 (UMLS CUI [1,2])
C4319828 (UMLS CUI [1,3])
C0683323 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
C0007820 (UMLS CUI [3,1])
C0205404 (UMLS CUI [3,2])
C0205318 (UMLS CUI [3,3])
C0027051 (UMLS CUI [4])
C0027765 (UMLS CUI [5])
C0004936 (UMLS CUI [6])