Age
Item
1. ages 25-39 and 65-79 years old
boolean
C0001779 (UMLS CUI [1])
Major Depressive Disorder | Major depressive disorder, recurrent
Item
2. major depressive disorder (mdd), single or recurrent, as diagnosed by the prime-md
boolean
C1269683 (UMLS CUI [1])
C0154409 (UMLS CUI [2])
Montgomery-Asberg Depression Rating Scale Questionnaire
Item
3. madrs ≥ 15
boolean
C4054475 (UMLS CUI [1])
Residence Nearby
Item
4. in-town and available to commute to oakland for a 12-week period
boolean
C0237096 (UMLS CUI [1,1])
C1706276 (UMLS CUI [1,2])
Participation Exercise intervention Moderate intensity
Item
5. study nurse practitioner approval to participate in a 12-week moderate intense exercise intervention
boolean
C0679823 (UMLS CUI [1,1])
C1831738 (UMLS CUI [1,2])
C4081855 (UMLS CUI [1,3])
Patients Eligible Magnetic Resonance Imaging
Item
6. eligible to undergo mri
boolean
C0030705 (UMLS CUI [1,1])
C1548635 (UMLS CUI [1,2])
C0024485 (UMLS CUI [1,3])
Informed Consent Unable
Item
1. inability to provide informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Modified Mini-Mental State Examination score | Dementia Poor performance status Neuropsychological testing battery | Dementia Poor performance status IQCODE questionnaire | Dementia Clinical information
Item
2. modified mini-mental score (3ms) less than 84 or dementia based upon dsm-iv criteria including poor performance on the clinical neuropsychological battery, iqcode, and all available clinical information.
boolean
C4304091 (UMLS CUI [1])
C0497327 (UMLS CUI [2,1])
C1831741 (UMLS CUI [2,2])
C2121096 (UMLS CUI [2,3])
C0497327 (UMLS CUI [3,1])
C1831741 (UMLS CUI [3,2])
C3836253 (UMLS CUI [3,3])
C0497327 (UMLS CUI [4,1])
C2708733 (UMLS CUI [4,2])
Bipolar I disorder Lifetime | Bipolar II disorder Lifetime | Schizophrenia Lifetime | Schizoaffective Disorder Lifetime | Schizophreniform Disorders Lifetime | Delusional disorder Lifetime | Psychotic symptom
Item
3. lifetime diagnosis of bipolar i or ii disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder, or current psychotic symptoms.
boolean
C0853193 (UMLS CUI [1,1])
C4071830 (UMLS CUI [1,2])
C0236788 (UMLS CUI [2,1])
C4071830 (UMLS CUI [2,2])
C0036341 (UMLS CUI [3,1])
C4071830 (UMLS CUI [3,2])
C0036337 (UMLS CUI [4,1])
C4071830 (UMLS CUI [4,2])
C0036358 (UMLS CUI [5,1])
C4071830 (UMLS CUI [5,2])
C0011251 (UMLS CUI [6,1])
C4071830 (UMLS CUI [6,2])
C0871189 (UMLS CUI [7])
Substance Use Disorders | Substance Dependence
Item
4. abuse of or dependence on alcohol or other substances within the past three months
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
High suicide risk | Feeling suicidal | Suicidal intent | Planning suicide | Disease Management Receive Unable | Hospitalization Unwilling | Referral to psychiatric hospital Urgent
Item
5. high risk for suicide (e.g., active si and/or current/recent intent or plan) and unable to be managed safely in the clinical trial (e.g., unwilling to be hospitalized). urgent psychiatric referral will be made in these cases.
boolean
C1271074 (UMLS CUI [1])
C0424000 (UMLS CUI [2])
C0582496 (UMLS CUI [3])
C0424001 (UMLS CUI [4])
C0376636 (UMLS CUI [5,1])
C1514756 (UMLS CUI [5,2])
C1299582 (UMLS CUI [5,3])
C0019993 (UMLS CUI [6,1])
C0558080 (UMLS CUI [6,2])
C0850341 (UMLS CUI [7,1])
C0439609 (UMLS CUI [7,2])
Medical contraindication Venlafaxine XR | Intolerance to Venlafaxine XR U/day
Item
6. contraindication to venlafaxine xr as determined by study physician including history of intolerance of venlafaxine xr in the study target dosage range (venlafaxine xr at up to 300 mg/day).
boolean
C1301624 (UMLS CUI [1,1])
C0078569 (UMLS CUI [1,2])
C1707968 (UMLS CUI [1,3])
C1744706 (UMLS CUI [2,1])
C0078569 (UMLS CUI [2,2])
C1707968 (UMLS CUI [2,3])
C0456683 (UMLS CUI [2,4])
Lacking Able to communicate English Language
Item
7. inability to communicate in english (i.e., interview cannot be conducted without an interpreter; subject largely unable to understand questions and cannot respond in english).
boolean
C0332268 (UMLS CUI [1,1])
C2364293 (UMLS CUI [1,2])
C0376245 (UMLS CUI [1,3])
Hypesthesia | Correction Unsuccessful
Item
8. non-correctable clinically significant sensory impairment (i.e., cannot hear well enough to cooperate with interview)
boolean
C0020580 (UMLS CUI [1])
C1947976 (UMLS CUI [2,1])
C1272705 (UMLS CUI [2,2])
Illness Unstable | Illness Uncontrolled | Delirium | Hypertensive disease | Hyperlipidemia | Risk factors Cerebrovascular | Cardiovascular risk factor
Item
9. unstable/uncontrolled medical illness, including delirium, hypertension, hyperlipidemia, or cerebrovascular or cardiovascular risk factors that are not under medical management.
boolean
C0221423 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0221423 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0011206 (UMLS CUI [3])
C0020538 (UMLS CUI [4])
C0020473 (UMLS CUI [5])
C0035648 (UMLS CUI [6,1])
C1880018 (UMLS CUI [6,2])
C0850624 (UMLS CUI [7])
Psychotropic Drugs
Item
10. subjects taking psychotropic medications that cannot be safely tapered or discontinued prior to study initiation
boolean
C0033978 (UMLS CUI [1])
Venlafaxine U/day failed
Item
11. if a patient failed a trial of venlafaxine (12 weeks of treatment with venlafaxine including at least 6 weeks on 300mg/day), he/she would not be eligible.
boolean
C0078569 (UMLS CUI [1,1])
C0456683 (UMLS CUI [1,2])
C0231175 (UMLS CUI [1,3])
Pharmaceutical Preparations Affecting GABA Receptors | Kava preparation | Valerian root extract | theanine | GABA Supplements
Item
12. other drugs that may affect the gaba system will be excluded (e.g., kava, valerian, theanine, and gaba supplements).
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0206518 (UMLS CUI [1,3])
C0939882 (UMLS CUI [2])
C0795674 (UMLS CUI [3])
C0076380 (UMLS CUI [4])
C0016904 (UMLS CUI [5,1])
C0242295 (UMLS CUI [5,2])
Linezolid To be stopped | Zyvox To be stopped
Item
13. the drug linezolid (zyvox) should be discontinued prior to study enrollment and should not be used during the study.
boolean
C0663241 (UMLS CUI [1,1])
C1272691 (UMLS CUI [1,2])
C0876226 (UMLS CUI [2,1])
C1272691 (UMLS CUI [2,2])
Exclusion Criteria MRI scan | Artificial cardiac pacemaker | Aneurysm clip | Cochlear Implants | Pregnancy | Intrauterine Devices | Shrapnel | Metal foreign body in eye region | Neurostimulator | Excessive body weight gain | Tinnitus | Claustrophobia
Item
14. exclusion criteria for mr scans include: cardiac pacemaker, aneurysm clip, cochlear implant, pregnancy, iud, shrapnel, history of metal fragments in the eye, neurostimulators, weight >250 lbs., tinnitus, or claustrophobia.
boolean
C0680251 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0030163 (UMLS CUI [2])
C0179977 (UMLS CUI [3])
C0009199 (UMLS CUI [4])
C0032961 (UMLS CUI [5])
C0021900 (UMLS CUI [6])
C0522670 (UMLS CUI [7])
C0562528 (UMLS CUI [8])
C0582124 (UMLS CUI [9])
C0000765 (UMLS CUI [10])
C0040264 (UMLS CUI [11])
C0008909 (UMLS CUI [12])
Medical condition Affecting Equilibrium | Medical condition Affecting Gait | Treatment Affecting Equilibrium | Treatment Affecting Gait | Medical contraindication Physical activity Moderate intensity
Item
15. current medical condition or treatment for a medical condition that could affect balance, gait, or contraindicate participation in moderate intensity physical activity.
boolean
C3843040 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0014653 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0016928 (UMLS CUI [2,3])
C0087111 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C0014653 (UMLS CUI [3,3])
C0087111 (UMLS CUI [4,1])
C0392760 (UMLS CUI [4,2])
C0016928 (UMLS CUI [4,3])
C1301624 (UMLS CUI [5,1])
C0026606 (UMLS CUI [5,2])
C4081855 (UMLS CUI [5,3])
Gait Condition | Use of Walking assistive device | Medical contraindication Treadmill Exercise test
Item
16. observed gait condition or use of walking assisted device that would contraindicate use of treadmill for exercise testing and intervention.
boolean
C0016928 (UMLS CUI [1,1])
C0348080 (UMLS CUI [1,2])
C1524063 (UMLS CUI [2,1])
C3874140 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C0184069 (UMLS CUI [3,2])
C0015260 (UMLS CUI [3,3])
Congestive heart failure | Angina Pectoris | Cardiac Arrhythmia Uncontrolled | Symptoms At risk Cardiovascular event | Myocardial Infarction | Coronary Artery Bypass Surgery | Angioplasty | Condition Requirement Chronic anticoagulation | Deep Vein Thrombosis
Item
17. current congestive heart failure, angina, uncontrolled arrhythmia, or other symptoms indicative of an increased acute risk for a cardiovascular event; within the previous 12 months having a myocardial infarction, coronary artery bypass grafting, or angioplasty; conditions requiring chronic anticoagulation (i.e. recent or recurrent dvt).
boolean
C0018802 (UMLS CUI [1])
C0002962 (UMLS CUI [2])
C0003811 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
C1457887 (UMLS CUI [4,1])
C1444641 (UMLS CUI [4,2])
C1320716 (UMLS CUI [4,3])
C0027051 (UMLS CUI [5])
C0010055 (UMLS CUI [6])
C0162577 (UMLS CUI [7])
C0348080 (UMLS CUI [8,1])
C1514873 (UMLS CUI [8,2])
C0694554 (UMLS CUI [8,3])
C0149871 (UMLS CUI [9])
Eating Disorders | Medical contraindication Physical activity
Item
18. eating disorders that would contraindicate physical activity.
boolean
C0013473 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0026606 (UMLS CUI [2,2])
Exercise Duration/Frequency
Item
19. report exercise on more than three days per week for greater than 20 minutes per day over the past three months.
boolean
C0015259 (UMLS CUI [1,1])
C3669316 (UMLS CUI [1,2])
Relocation of home Planned | Commitment Preventing Protocol Compliance
Item
20. report plans to relocate to a location not accessible to the study site or having employment, personal, or travel commitments that prohibit attendance to at least 80 percent of the scheduled intervention sessions and all of the scheduled assessments.
boolean
C2699029 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C0870312 (UMLS CUI [2,1])
C1292733 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus, Non-Insulin-Dependent
Item
21. current type i or ii diabetes
boolean
C0011854 (UMLS CUI [1])
C0011860 (UMLS CUI [2])