Cutaneous T-Cell Lymphoma Ann Arbor lymphoma staging system | Patients Appropriate Total Skin Electron Beam Radiation Therapy
Item
1. the stage i-iv cutaneous t-cell lymphoma (ctcl) of international society cutaneous lymphomas (iscl) and u.s. cutaneous lymphoma consortium (usclc)/european organization for research & treatment of cancer (eortc), patients who are candidates for tseb by recommendation of national comprehensive cancer network guidelines (version 4.2011, mycosis fungoid/sezary syndrome)
boolean
C0079773 (UMLS CUI [1,1])
C0432516 (UMLS CUI [1,2])
C0030705 (UMLS CUI [2,1])
C1548787 (UMLS CUI [2,2])
C2985561 (UMLS CUI [2,3])
Patients Unresponsive to Treatment | UV Radiation Topical Unsuccessful | Interferon-alpha Unsuccessful | PUVA Photochemotherapy Unsuccessful | Isotretinoin Unsuccessful | Chemotherapy Unsuccessful
Item
2. patients who are refractory or not feasible to the topic uv irradiation, interferon alpha, psoralen plus ultraviolet a photochemotherapy, and isotretinoin or chemotherapy.
boolean
C0030705 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C4319812 (UMLS CUI [2,1])
C0332237 (UMLS CUI [2,2])
C1272705 (UMLS CUI [2,3])
C0002199 (UMLS CUI [3,1])
C1272705 (UMLS CUI [3,2])
C0853073 (UMLS CUI [4,1])
C1272705 (UMLS CUI [4,2])
C0022265 (UMLS CUI [5,1])
C1272705 (UMLS CUI [5,2])
C0392920 (UMLS CUI [6,1])
C1272705 (UMLS CUI [6,2])
Karnofsky Performance Status | Creatinine clearance measurement | Left ventricular ejection fraction | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Pulmonary function | Forced expiratory volume procedure | Peripheral Neuropathy CTCAE Grades | Able to lie down Supine Position Duration
Item
3. eligibility criteria included the following: karnofsky status 70% or greater; creatinine clearance greater than 50 ml/min; cardiac left ventricular ejection fraction 50% or greater; aspartate aminotransferase and alanine aminotransferase less than 2.5 times the upper limits of institutional normal; adequate pulmonary function as shown by a forced expiratory volume of greater than 60%; and peripheral neuropathy grade 1 or lower. patients were preassessed for their ability to lie supine for approximately 1 hour.
boolean
C0206065 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
C0428772 (UMLS CUI [3])
C0201899 (UMLS CUI [4])
C0201836 (UMLS CUI [5])
C0231921 (UMLS CUI [6])
C1306036 (UMLS CUI [7])
C0031117 (UMLS CUI [8,1])
C1516728 (UMLS CUI [8,2])
C0560841 (UMLS CUI [9,1])
C0038846 (UMLS CUI [9,2])
C0449238 (UMLS CUI [9,3])
Total Skin Electron Beam Radiation Therapy Absent | Therapeutic radiology procedure Local allowed
Item
4. they had to be previously untreated tsebt. prior local radiation was permitted.
boolean
C2985561 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1522449 (UMLS CUI [2,1])
C0205276 (UMLS CUI [2,2])
C0683607 (UMLS CUI [2,3])
Informed Consent
Item
5. all patients voluntarily signed an informed consent form approved by the institutional review board.
boolean
C0021430 (UMLS CUI [1])
Total Skin Electron Beam Radiation Therapy Cutaneous T-Cell Lymphoma | Cancer Other | Cardiac function test abnormal | Cardiac ejection fraction Systolic | Cardiac stress test abnormal | Chronic disease of respiratory system | Reduced vital capacity | Decreased carbon monoxide diffusion capacity | Liver Dysfunction | Serum total bilirubin measurement | Alanine aminotransferase increased | Aspartate aminotransferase increased | Mental disorders
Item
1. patient were prior treated by tsebt for ctcl, another type of cancer, abnormal cardiac function (systolic ejection fraction < 50 percent or an abnormal stress test), chronic respiratory disease (vital capacity or carbon monoxide diffusion, < 50 percent of normal), abnormal liver function (serum bilirubin, > 2.0 mg per deciliter [>35 micromol per liter]; or serum aminotransferase values more than four times the normal value), and psychiatric disease.
boolean
C2985561 (UMLS CUI [1,1])
C0079773 (UMLS CUI [1,2])
C1707251 (UMLS CUI [2])
C0438177 (UMLS CUI [3])
C0232174 (UMLS CUI [4,1])
C0039155 (UMLS CUI [4,2])
C1096350 (UMLS CUI [5])
C0264220 (UMLS CUI [6])
C0476408 (UMLS CUI [7])
C3806331 (UMLS CUI [8])
C0086565 (UMLS CUI [9])
C1278039 (UMLS CUI [10])
C0151905 (UMLS CUI [11])
C0151904 (UMLS CUI [12])
C0004936 (UMLS CUI [13])
Pregnancy | Breast Feeding | Pregnancy, Planned
Item
2. females who are pregnant/lactating or planning to be pregnant.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Systemic disease | Requirement Glucocorticoids Long-term | Requirement Immunosuppressive Agents Long-term
Item
3. patients with other systemic diseases that required long-term (≥ 2 weeks) usage of glucocorticosteroid or immunosuppressant agent(s) within 4 weeks prior to the initiation of study treatment.
boolean
C0442893 (UMLS CUI [1])
C1514873 (UMLS CUI [2,1])
C0017710 (UMLS CUI [2,2])
C0443252 (UMLS CUI [2,3])
C1514873 (UMLS CUI [3,1])
C0021081 (UMLS CUI [3,2])
C0443252 (UMLS CUI [3,3])
Child | Handicap
Item
4. child or handicap are excluded
boolean
C0008059 (UMLS CUI [1])
C0231172 (UMLS CUI [2])