Informed Consent
Item
provision of informed consent prior to any study specific procedures
boolean
C0021430 (UMLS CUI [1])
Age
Item
age between 18 and 75 years
boolean
C0001779 (UMLS CUI [1])
Diabetes Mellitus, Non-Insulin-Dependent
Item
type 2 dm according to ada criteria
boolean
C0011860 (UMLS CUI [1])
Coronary Artery Disease Angiography
Item
angiographically documented cad
boolean
C1956346 (UMLS CUI [1,1])
C0002978 (UMLS CUI [1,2])
Aspirin chronic
Item
chronic treatment (>1 month) with aspirin (100mg/day)
boolean
C0004057 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
Aspirin allergy | Hypersensitivity Clopidogrel | Hypersensitivity Ticagrelor
Item
known allergies to aspirin, clopidogrel, or ticagrelor
boolean
C0004058 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C0070166 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C1999375 (UMLS CUI [3,2])
Hematological Disease
Item
blood dyscrasia
boolean
C0018939 (UMLS CUI [1])
Acute Coronary Syndrome | Hemodynamic instability
Item
any recent acute coronary syndrome (<30 days) or hemodinamic instability
boolean
C0948089 (UMLS CUI [1])
C0948268 (UMLS CUI [2])
Antiplatelet therapy | Exception Aspirin | Thienopyridines | cilostazol | Dipyridamole | Platelet Glycoprotein IIb/IIIA Inhibitors
Item
recent antiplatelet therapy (<14 days), with the exception of asa, including: thienopyridines, cilostazol, dipiridamol, glycoprotein iib/iiia inhibitors
boolean
C1096021 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0004057 (UMLS CUI [2,2])
C2936588 (UMLS CUI [3])
C0055729 (UMLS CUI [4])
C0012582 (UMLS CUI [5])
C1373125 (UMLS CUI [6])
Anticoagulation Therapy Oral | Coumarin Derivative
Item
oral anticoagulation with a coumarin derivative
boolean
C0003281 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0010206 (UMLS CUI [2,1])
C1527240 (UMLS CUI [2,2])
CYP3A4 Inhibitor | Ketoconazole | Clarithromycin | nefazodone | Ritonavir | Atazanavir
Item
concomitant treatment with a potent cyp3a4 inhibitor (e.g. ketoconazole, claritromicine, nefazodone, ritonavir, atazanavir)
boolean
C3830624 (UMLS CUI [1])
C0022625 (UMLS CUI [2])
C0055856 (UMLS CUI [3])
C0068485 (UMLS CUI [4])
C0292818 (UMLS CUI [5])
C1145759 (UMLS CUI [6])
Hemorrhage
Item
any active bleeding
boolean
C0019080 (UMLS CUI [1])
Cerebrovascular accident | Transient Ischemic Attack | Intracranial Hemorrhages
Item
recent history of stroke, tia or intracranial bleeding (<6 months prior to inclusion)
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
C0151699 (UMLS CUI [3])
Platelet Count measurement
Item
platelet count <100x106/microl
boolean
C0032181 (UMLS CUI [1])
Chronic Kidney Disease Severe | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
severe chronic kidney disease (creatinine clearance measured with cockcroft-gault formula <30ml/min)
boolean
C1561643 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C2711451 (UMLS CUI [2])
Neoplasms
Item
any active neoplasm
boolean
C0027651 (UMLS CUI [1])
Alanine aminotransferase increased
Item
baseline alt >2.5 times the upper limit of normality
boolean
C0151905 (UMLS CUI [1])
Pregnancy | Childbirth
Item
pregnant or childbearing females
boolean
C0032961 (UMLS CUI [1])
C1148523 (UMLS CUI [2])