Resident United States
Item
patients must be a permanent resident of the united states
boolean
C2347958 (UMLS CUI [1,1])
C0041703 (UMLS CUI [1,2])
Hemodynamics Parameters Catheterization of right heart
Item
documentation of the following hemodynamic parameters by right heart catheterization
boolean
C0019010 (UMLS CUI [1,1])
C0449381 (UMLS CUI [1,2])
C0189896 (UMLS CUI [1,3])
Mean pulmonary arterial pressure At rest
Item
mean pulmonary arterial pressure (papm) ≥ 25 mm hg at rest and,
boolean
C3854605 (UMLS CUI [1,1])
C0443144 (UMLS CUI [1,2])
Pulmonary Wedge Pressure
Item
pulmonary artery wedge pressure (pawp) ≤ 15 mm hg (or > 15 mmhg if justified)
boolean
C0034094 (UMLS CUI [1])
Thromboembolism chronic Cause Pulmonary Hypertension | Diagnostic radiologic examination
Item
radiologic confirmation that chronic thromboembolic disease is the cause of the pulmonary hypertension by
boolean
C0040038 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0015127 (UMLS CUI [1,3])
C0020542 (UMLS CUI [1,4])
C0043299 (UMLS CUI [2])
Mismatch Lung perfusion defect Quantity Ventilation perfusion scan
Item
one or more mismatched perfusion defect(s) by lung ventilation/perfusion scan, and
boolean
C1881865 (UMLS CUI [1,1])
C4028623 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0560738 (UMLS CUI [1,4])
Thromboembolism chronic | Pulmonary artery band | Vascular stenosis CT pulmonary angiogram | Vessel occlusion CT pulmonary angiogram | Vascular stenosis Angiography | Vessel occlusion Angiography | Vascular stenosis Magnetic Resonance Angiography | Vessel occlusion Magnetic Resonance Angiography
Item
confirmation of chronic thromboembolic disease by evidence of bands/webs, vessel narrowing or occlusion seen on ct pulmonary angiogram (cta), conventional angiography or mr angiography (mra).
boolean
C0040038 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C2022612 (UMLS CUI [2])
C0679403 (UMLS CUI [3,1])
C4286018 (UMLS CUI [3,2])
C1386685 (UMLS CUI [4,1])
C4286018 (UMLS CUI [4,2])
C0679403 (UMLS CUI [5,1])
C0002978 (UMLS CUI [5,2])
C1386685 (UMLS CUI [6,1])
C0002978 (UMLS CUI [6,2])
C0679403 (UMLS CUI [7,1])
C0243032 (UMLS CUI [7,2])
C1386685 (UMLS CUI [8,1])
C0243032 (UMLS CUI [8,2])
Chronic thromboembolic pulmonary hypertension | Thromboembolism chronic Cause Pulmonary Hypertension | V/Q scan Abnormal | Thromboembolism chronic CT pulmonary angiogram | Thromboembolism chronic Magnetic Resonance Angiography | Thromboembolism chronic Pulmonary angiography
Item
patients must be diagnosed with cteph within 6 months of being considered for study eligibility (signing of consent to participate). the date of diagnosis will be defined as when both hemodynamic criteria have been met and chronic thromboembolic disease is confirmed to be the cause of the pulmonary hypertension by an abnormal v/q scan and the presence of chronic thromboembolic disease on cta, mra or pulmonary angiography. hemodynamic and radiologic criteria can be met at separate time points; the most recently met criteria time point will be defined as the date of diagnosis.
boolean
C2363973 (UMLS CUI [1])
C0040038 (UMLS CUI [2,1])
C0205191 (UMLS CUI [2,2])
C0015127 (UMLS CUI [2,3])
C0020542 (UMLS CUI [2,4])
C0560738 (UMLS CUI [3,1])
C0205161 (UMLS CUI [3,2])
C0040038 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
C4286018 (UMLS CUI [4,3])
C0040038 (UMLS CUI [5,1])
C0205191 (UMLS CUI [5,2])
C0243032 (UMLS CUI [5,3])
C0040038 (UMLS CUI [6,1])
C0205191 (UMLS CUI [6,2])
C0677490 (UMLS CUI [6,3])
Chronic thromboembolic pulmonary hypertension Confirmed by Adjudication Committee
Item
prior to enrollment all subjects must have the diagnosis of cteph confirmed by the adjudication committee.
boolean
C2363973 (UMLS CUI [1,1])
C0521093 (UMLS CUI [1,2])
C2700368 (UMLS CUI [1,3])
Informed Consent Unwilling | Informed Consent Unable
Item
patients unwilling or unable to provide written consent for participation in the study. appropriate surrogate consent will be obtained for pediatric patients as defined by each investigational site's irb.
boolean
C0021430 (UMLS CUI [1,1])
C0558080 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
Primary disorder | Life Expectancy
Item
patients with an underlying medical disorder with an anticipated life expectancy less than 2 years.
boolean
C0277554 (UMLS CUI [1])
C0023671 (UMLS CUI [2])
Lacking Inclusion criteria Fulfill
Item
patients who do not meet inclusion criteria including:
boolean
C0332268 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C1550543 (UMLS CUI [1,3])
Hemodynamics criteria Absent Catheterization of right heart
Item
have not had documentation of hemodynamic criteria by right heart catheterization as outlined in the inclusion criteria
boolean
C0019010 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0189896 (UMLS CUI [1,4])
Thromboembolism chronic | Diagnostic radiologic examination Absent
Item
do not have radiologic confirmation of chronic thromboembolic disease as outlined in the inclusion criteria
boolean
C0040038 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0043299 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Inclusion criteria Fulfill WHO Groups
Item
meet the criteria for inclusion into who groups i, ii, iii, or v
boolean
C1512693 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
C0043237 (UMLS CUI [1,3])
C0441833 (UMLS CUI [1,4])