Gender | Female infertility | Age | Body mass index
Item
male or female (of non-child bearing potential) between 18 and 70 years of age with body mass index ≥18 to <38 kg/m2.
boolean
C0079399 (UMLS CUI [1])
C0021361 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
C1305855 (UMLS CUI [4])
Chronic Hepatitis C Genotype | Antiviral Therapy Absent Hepatitis C virus
Item
chronic hcv genotype 3 infection prior to study enrollment and has never received antiviral treatment for hcv.
boolean
C0524910 (UMLS CUI [1,1])
C0017431 (UMLS CUI [1,2])
C0280274 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0220847 (UMLS CUI [2,3])
Plasma Hepatitis C virus RNA assay
Item
subject has plasma hcv rna level > 10,000 iu/ml at screening.
boolean
C0032105 (UMLS CUI [1,1])
C1272251 (UMLS CUI [1,2])
Gender Sexually active Infertility | Partner Male | Gender Sexually active Contraceptive methods Quantity
Item
sexually active males must be sterile, have male partners only, or agree to use two effective forms of birth control for 7 months after stopping study drug.
boolean
C0079399 (UMLS CUI [1,1])
C0241028 (UMLS CUI [1,2])
C0021359 (UMLS CUI [1,3])
C0682323 (UMLS CUI [2,1])
C0086582 (UMLS CUI [2,2])
C0079399 (UMLS CUI [3,1])
C0241028 (UMLS CUI [3,2])
C0700589 (UMLS CUI [3,3])
C1265611 (UMLS CUI [3,4])
Drug Allergy Severe | Drug Allergy Life Threatening | Drug Allergy Significant
Item
history of severe, life-threatening or other significant sensitivity to any drug.
boolean
C0013182 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0013182 (UMLS CUI [2,1])
C2826244 (UMLS CUI [2,2])
C0013182 (UMLS CUI [3,1])
C0750502 (UMLS CUI [3,2])
Hepatitis B surface antigen positive | HIV antibody positive
Item
positive test result for hepatitis b surface antigen (hbsag) or anti-human immunodeficiency virus antibody (hiv ab).
boolean
C0149709 (UMLS CUI [1])
C0920548 (UMLS CUI [2])
Prior Therapy Hepatitis C virus
Item
prior therapy for the treatment of hcv.
boolean
C1514463 (UMLS CUI [1,1])
C0220847 (UMLS CUI [1,2])
Liver Cirrhosis | Liver Cirrhosis In the past
Item
any current or past clinical evidence of cirrhosis.
boolean
C0023890 (UMLS CUI [1])
C0023890 (UMLS CUI [2,1])
C1444637 (UMLS CUI [2,2])
Liver disease Cause Any | Exception Chronic Hepatitis C
Item
any cause of liver disease other than chronic hcv-infection.
boolean
C0023895 (UMLS CUI [1,1])
C0015127 (UMLS CUI [1,2])
C1552551 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C0524910 (UMLS CUI [2,2])
HCV coinfection Genotype | Hepatitis C virus genotype Other
Item
hcv genotype co-infection with any other hcv genotype.
boolean
C1698259 (UMLS CUI [1,1])
C0017431 (UMLS CUI [1,2])
C1148363 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Pharmaceutical Preparations Contraindicated
Item
use of contraindicated medications within 2 weeks or 10 half-lives of dosing.
boolean
C0013227 (UMLS CUI [1,1])
C1444657 (UMLS CUI [1,2])