Implantation of left ventricular assist device | Chronic heart failure
Item
patients that have had a left ventricular assist device (lvad) implanted for chronic heart failure, where chronic heart failure is defined as at least 6 months
boolean
C0397130 (UMLS CUI [1])
C0264716 (UMLS CUI [2])
Clinical status Stable
Item
patients are clinically stable in the opinion of the clinical team looking after the patient
boolean
C0449440 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
<18 or >70 years of age at the time of consent
boolean
C0001779 (UMLS CUI [1])
Pregnancy | Birth
Item
pregnancy or within 6 months of giving birth
boolean
C0032961 (UMLS CUI [1])
C0005615 (UMLS CUI [2])
Childbearing Potential Contraceptive methods Absent
Item
women of child-bearing potential not using an effective method of contraception
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Gender Contraceptive methods Absent
Item
men not using an effective method of contraception
boolean
C0079399 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Virus Disease Suspected | Mycoses Suspected | Parasitic infection Suspected
Item
suspected or active viral, fungal or parasitic infection within 48 hours prior to administration of imp, in the opinion of the investigator*.
boolean
C0042769 (UMLS CUI [1,1])
C0750491 (UMLS CUI [1,2])
C0026946 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
C0747256 (UMLS CUI [3,1])
C0750491 (UMLS CUI [3,2])
High risk of Thrombosis
Item
patients at a high risk of thrombosis in the opinion of the investigator
boolean
C0332167 (UMLS CUI [1,1])
C0040053 (UMLS CUI [1,2])
Episode Previous LVAD Thrombosis
Item
patients with a previous episode of lvad thrombosis
boolean
C0332189 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0181598 (UMLS CUI [1,3])
C0040053 (UMLS CUI [1,4])
Serum lactate dehydrogenase level elevated Persistent
Item
patients with persistently raised lactate dehydrogenase (ldh >2.5 uln)
boolean
C1275604 (UMLS CUI [1,1])
C0205322 (UMLS CUI [1,2])
Patient need for Anticoagulation Therapy Triple | Warfarin | Antiplatelet Agents Dual
Item
patients requiring triple anticoagulation i.e. warfarin and dual anti-platelet
boolean
C0686904 (UMLS CUI [1,1])
C0003281 (UMLS CUI [1,2])
C0205174 (UMLS CUI [1,3])
C0043031 (UMLS CUI [2])
C0085826 (UMLS CUI [3,1])
C0205173 (UMLS CUI [3,2])
Study Subject Participation Status
Item
patients participating in another clinical trial
boolean
C2348568 (UMLS CUI [1])
Protocol Compliance Unable
Item
patients unable to comply with the protocol mandated procedures for social or other reasons, in the opinion of the investigator and primary care physician
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Communicable Disease
Item
eligible, enrolled and randomised patients who develop an infection will have study treatment delayed until 7 or more days after the time point when infection is no longer clinically evident.
boolean
C0009450 (UMLS CUI [1])