Age
Item
age 30 to 70 years at beginning of study
boolean
C0001779 (UMLS CUI [1])
Low density lipoprotein cholesterol measurement
Item
ldl-cholesterol between 120 and 160 mg/dl
boolean
C0202117 (UMLS CUI [1])
Risk factors Quantity Coronary heart disease | Blood pressure determination | Antihypertensive Agents | Serum HDL cholesterol measurement | Age | Gender | FH: premature coronary heart disease | Coronary heart disease First Degree Relative
Item
less than 2+ risk factors for coronary heart disease (risk factors include: blood pressure > 140/90 mm hg or on blood pressure medication; hdl-cholesterol < 40 mg/dl; age greater than 45 yrs for males & greater than 55 yrs for females; family history of premature coronary heart disease (chd in male first degree relative <55 years; chd in female first degree relative <65 years)
boolean
C0035648 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0010068 (UMLS CUI [1,3])
C0005824 (UMLS CUI [2])
C0003364 (UMLS CUI [3])
C0428472 (UMLS CUI [4])
C0001779 (UMLS CUI [5])
C0079399 (UMLS CUI [6])
C1277208 (UMLS CUI [7])
C0010068 (UMLS CUI [8,1])
C1517194 (UMLS CUI [8,2])
Kidney Diseases | Liver diseases | Gout | Hyperthyroidism | Hypothyroidism Untreated | Hypothyroidism Unstable | Malignant Neoplasms | Gastrointestinal Diseases | Pancreatic Diseases | Metabolic Diseases | Malabsorption Syndrome
Item
presence of kidney disease, liver disease, gout, hyperthyroidism, untreated or unstable hypothyroidism, certain cancers, gastrointestinal disease, pancreatic disease, other metabolic diseases, or malabsorption syndromes
boolean
C0022658 (UMLS CUI [1])
C0023895 (UMLS CUI [2])
C0018099 (UMLS CUI [3])
C0020550 (UMLS CUI [4])
C0020676 (UMLS CUI [5,1])
C0332155 (UMLS CUI [5,2])
C0020676 (UMLS CUI [6,1])
C0443343 (UMLS CUI [6,2])
C0006826 (UMLS CUI [7])
C0017178 (UMLS CUI [8])
C0030286 (UMLS CUI [9])
C0025517 (UMLS CUI [10])
C0024523 (UMLS CUI [11])
Pharmaceutical Preparations Changing Lipid Metabolism | Non-Prescription Drugs Changing Lipid Metabolism | Supplements Changing Lipid Metabolism
Item
use of prescription or over-the-counter medications or supplements that alter lipid metabolism.
boolean
C0013227 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
C0598783 (UMLS CUI [1,3])
C0013231 (UMLS CUI [2,1])
C0392747 (UMLS CUI [2,2])
C0598783 (UMLS CUI [2,3])
C0242295 (UMLS CUI [3,1])
C0392747 (UMLS CUI [3,2])
C0598783 (UMLS CUI [3,3])
Birth
Item
women who have given birth during the previous 12 months
boolean
C0005615 (UMLS CUI [1])
Pregnancy | Pregnancy, Planned
Item
pregnant women or women who plan to become pregnant or become pregnant during the study
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Breast Feeding
Item
lactating women
boolean
C0006147 (UMLS CUI [1])
Non-Insulin-Dependent Diabetes Mellitus Requirement Antidiabetics Oral | Non-Insulin-Dependent Diabetes Mellitus Requirement Insulin
Item
type 2 diabetes requiring the use of oral antidiabetic agents or insulin
boolean
C0011860 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0935929 (UMLS CUI [1,3])
C1527415 (UMLS CUI [1,4])
C0011860 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0021641 (UMLS CUI [2,3])
Bariatric Surgery | Operative Surgical Procedures Weight loss Related
Item
history of bariatric or certain other surgeries related to weight control
boolean
C1456587 (UMLS CUI [1])
C0543467 (UMLS CUI [2,1])
C1262477 (UMLS CUI [2,2])
C0439849 (UMLS CUI [2,3])
Anti-Obesity Agents Prescription | Anti-Obesity Agents Non-Prescription | Dietary Supplements Against Obesity | Phenylpropanolamine | Ephedrine | Caffeine | Obesity surgery
Item
use of prescription or over-the-counter antiobesity medications or supplements (e.g., phenylpropanolamine, ephedrine, caffeine) during and for at least 6 months prior to the start of the study or a history of a surgical intervention for obesity
boolean
C0376607 (UMLS CUI [1,1])
C0033080 (UMLS CUI [1,2])
C0376607 (UMLS CUI [2,1])
C0013231 (UMLS CUI [2,2])
C0242295 (UMLS CUI [3,1])
C0521124 (UMLS CUI [3,2])
C0028754 (UMLS CUI [3,3])
C0031495 (UMLS CUI [4])
C0014479 (UMLS CUI [5])
C0006644 (UMLS CUI [6])
C1167841 (UMLS CUI [7])
Avoidance Herbal Supplements Unwilling
Item
unwillingness to abstain from herbal supplements for two weeks prior to the study and during the study
boolean
C0870186 (UMLS CUI [1,1])
C1504473 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
Tobacco use
Item
smokers or other tobacco users (during 6 months prior to the start of the study)
boolean
C0543414 (UMLS CUI [1])
Eating Disorders Inconsistent Dietary intervention | Dietary Patterns Inconsistent Dietary intervention | Vegetarians | Very low fat diet | Diet, High-Protein
Item
history of eating disorders or other dietary patterns which are not consistent with the dietary intervention (e.g., vegetarians, very low fat diets, high protein diets)
boolean
C0013473 (UMLS CUI [1,1])
C0442809 (UMLS CUI [1,2])
C0086153 (UMLS CUI [1,3])
C1517289 (UMLS CUI [2,1])
C0442809 (UMLS CUI [2,2])
C0086153 (UMLS CUI [2,3])
C0042441 (UMLS CUI [3])
C0452296 (UMLS CUI [4])
C0425403 (UMLS CUI [5])
Hypersensitivity Clinical Trial Food | Adverse reaction Clinical Trial Food
Item
known (self-reported) allergy or adverse reaction to study foods
boolean
C0020517 (UMLS CUI [1,1])
C0008976 (UMLS CUI [1,2])
C0016452 (UMLS CUI [1,3])
C0559546 (UMLS CUI [2,1])
C0008976 (UMLS CUI [2,2])
C0016452 (UMLS CUI [2,3])
Cardiovascular Disease | Myocardial Infarction | Procedure on heart | Cardiac rehabilitation | Cerebrovascular accident | Transient Ischemic Attack | Therapeutic procedure Transient Ischemic Attack | Pulmonary Embolism
Item
active cardiovascular disease (such as a heart attack or procedure within the past three months or participation in a cardiac rehabilitation program within the last three months, stroke, or history/treatment for transient ischemic attacks in the past three months, or documented history of pulmonary embolus in the past six months)
boolean
C0007222 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C1279986 (UMLS CUI [3])
C0700431 (UMLS CUI [4])
C0038454 (UMLS CUI [5])
C0007787 (UMLS CUI [6])
C0087111 (UMLS CUI [7,1])
C0007787 (UMLS CUI [7,2])
C0034065 (UMLS CUI [8])
Informed Consent Unable | Informed Consent Unwilling | Communication Research Personnel Unable | Communication Research Personnel Unwilling
Item
unable or unwilling to give informed consent or communicate with study staff
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
C0009452 (UMLS CUI [3,1])
C0035173 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])
C0009452 (UMLS CUI [4,1])
C0035173 (UMLS CUI [4,2])
C0558080 (UMLS CUI [4,3])
Substance Use Disorders | Substance Abuse Treatment | Alcohol-substance abuse rehabilitation treatment
Item
self-report of alcohol or substance abuse within the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in alcoholics anonymous is not an exclusion)
boolean
C0038586 (UMLS CUI [1])
C2551443 (UMLS CUI [2])
C0947090 (UMLS CUI [3])
Medical condition Interferes with Study Subject Participation Status | Mental condition Interferes with Study Subject Participation Status | Factor Behavioral Interferes with Study Subject Participation Status | Medical condition Interferes with Protocol Compliance | Mental condition Interferes with Protocol Compliance | Factor Behavioral Interferes with Protocol Compliance
Item
other medical, psychiatric, or behavioral factors that in the judgment of the principal investigator may interfere with study participation or the ability to follow the intervention protocol
boolean
C3843040 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C3840291 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C2348568 (UMLS CUI [2,3])
C1521761 (UMLS CUI [3,1])
C0004927 (UMLS CUI [3,2])
C0521102 (UMLS CUI [3,3])
C2348568 (UMLS CUI [3,4])
C3843040 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0525058 (UMLS CUI [4,3])
C3840291 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0525058 (UMLS CUI [5,3])
C1521761 (UMLS CUI [6,1])
C0004927 (UMLS CUI [6,2])
C0521102 (UMLS CUI [6,3])
C0525058 (UMLS CUI [6,4])