Adult | Age | Basal cell carcinoma Orbital Advanced Locally | Basal cell carcinoma Periorbital Advanced Locally | Recurrent basal cell carcinoma Orbital | Recurrent basal cell carcinoma Periorbital | Basal cell carcinoma Medial canthus At risk Lacrimal drainage
Item
adult patients over 18 years of age with locally advanced or recurrent orbital or periorbital basal cell carcinoma (bcca), or a medial canthal bcca that threatens the lacrimal drainage system.
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0007117 (UMLS CUI [3,1])
C0699036 (UMLS CUI [3,2])
C0205179 (UMLS CUI [3,3])
C1517927 (UMLS CUI [3,4])
C0007117 (UMLS CUI [4,1])
C0230064 (UMLS CUI [4,2])
C0205179 (UMLS CUI [4,3])
C1517927 (UMLS CUI [4,4])
C1304307 (UMLS CUI [5,1])
C0699036 (UMLS CUI [5,2])
C1304307 (UMLS CUI [6,1])
C0230064 (UMLS CUI [6,2])
C0007117 (UMLS CUI [7,1])
C0229247 (UMLS CUI [7,2])
C1444641 (UMLS CUI [7,3])
C0423157 (UMLS CUI [7,4])
Assessment Clinical Score
Item
clinical assessment score obtained at baseline.
boolean
C1516048 (UMLS CUI [1,1])
C0205210 (UMLS CUI [1,2])
C0449820 (UMLS CUI [1,3])
Screening Oncologic
Item
medical oncology screening performed at baseline.
boolean
C1710032 (UMLS CUI [1,1])
C0205478 (UMLS CUI [1,2])
Basal cell carcinoma Size | Basal cell carcinoma Location
Item
adequate bcca size and location.
boolean
C0007117 (UMLS CUI [1,1])
C0456389 (UMLS CUI [1,2])
C0007117 (UMLS CUI [2,1])
C1515974 (UMLS CUI [2,2])
Capacity Hematopoietic | Liver function | Renal function
Item
adequate hematopoietic capacity, hepatic and renal function.
boolean
C1998319 (UMLS CUI [1,1])
C0229601 (UMLS CUI [1,2])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
Gender Male Condoms
Item
male patients must agree to use condoms during treatment and for 2 months after last dose.
boolean
C0079399 (UMLS CUI [1,1])
C0009653 (UMLS CUI [1,2])
Gender | Sperm donation Absent
Item
male patients must agree to not donate sperm during treatment and for 2 months after last dose.
boolean
C0079399 (UMLS CUI [1])
C0871414 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Blood Donation Absent
Item
participant must agree not to donate blood during the study and for 7 months after last dose.
boolean
C0005794 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Informed Consent
Item
informed consent signed.
boolean
C0021430 (UMLS CUI [1])
Blood Biomarker Analysis
Item
patient must consent to blood biomarker analysis.
boolean
C0005767 (UMLS CUI [1,1])
C0005516 (UMLS CUI [1,2])
C0002778 (UMLS CUI [1,3])
Patient Present Clinic Visits
Item
patient must be able to be present for monthly visits for the duration of the study.
boolean
C0030705 (UMLS CUI [1,1])
C0150312 (UMLS CUI [1,2])
C0008952 (UMLS CUI [1,3])
Lacking Able to swallow Capsule | Swallow Capsule Unwilling
Item
inability or unwillingness to swallow capsules.
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0006935 (UMLS CUI [1,3])
C4521686 (UMLS CUI [2,1])
C0006935 (UMLS CUI [2,2])
C0558080 (UMLS CUI [2,3])
Protocol Compliance Unable | Protocol Compliance Unwilling
Item
inability or unwillingness to comply with study procedures.
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnant, lactating, or breast feeding women.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Childbearing Potential
Item
women of childbearing potential.
boolean
C3831118 (UMLS CUI [1])
Illness Uncontrolled
Item
uncontrolled medical illness.
boolean
C0221423 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Age
Item
age under 18 years.
boolean
C0001779 (UMLS CUI [1])