Postmenopausal state | Age | Amenorrhea Duration
Item
postmenopausal women (as defined by age ≥45 years old or amenorrhea for >2years)
boolean
C0232970 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0002453 (UMLS CUI [3,1])
C0449238 (UMLS CUI [3,2])
Diabetes Mellitus, Non-Insulin-Dependent | Antidiabetics Absent | Metformin | Sulfonylurea | Insulin regime U/day
Item
type 2 dm currently not on diabetes-specific medication(s) or treated with monotherapy of metformin or a sulfonylurea. patients treated with insulin monotherapy will also be eligible if the total daily dose of insulin is ≤10units. if on a medication for diabetes prior to study entry, the medication can be discontinued for 2 weeks prior to study initiation.
boolean
C0011860 (UMLS CUI [1])
C0935929 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0025598 (UMLS CUI [3])
C0038766 (UMLS CUI [4])
C0557978 (UMLS CUI [5,1])
C0456683 (UMLS CUI [5,2])
Hemoglobin A1c measurement
Item
hemoglobin a1c (hba1c) of 6.5-9.0%
boolean
C0474680 (UMLS CUI [1])
Incretin mimetic product | exenatide | liraglutide | Dipeptidyl-Peptidase IV Inhibitors | sitagliptin | saxagliptin | Thiazolidinediones | Glucocorticoids Oral
Item
use of an incretin mimetic (i.e. exenatide, liraglutide), a dpp-4 inhibitor (i.e. sitagliptin, saxagliptin), a thiazolidinedione, or oral glucocorticoids in the 6 months prior to the study will not be eligible
boolean
C1562104 (UMLS CUI [1])
C0167117 (UMLS CUI [2])
C1456408 (UMLS CUI [3])
C1827106 (UMLS CUI [4])
C1565750 (UMLS CUI [5])
C1611934 (UMLS CUI [6])
C1257987 (UMLS CUI [7])
C0017710 (UMLS CUI [8,1])
C1527415 (UMLS CUI [8,2])
Osteoporosis | Pharmaceutical Preparations Osteoporosis Specific | Diphosphonates | Teriparatide | Estrogens | Selective Estrogen Receptor Modulators
Item
known osteoporosis or patients treated with an osteoporosis-specific medication (bisphosphonate, teriparatide) or estrogen (including selective estrogen receptor modulators (serms)) or those who anticipate imminent treatment with one of these medications will be excluded from the study
boolean
C0029456 (UMLS CUI [1])
C0013227 (UMLS CUI [2,1])
C0029456 (UMLS CUI [2,2])
C0205369 (UMLS CUI [2,3])
C0012544 (UMLS CUI [3])
C0070093 (UMLS CUI [4])
C0014939 (UMLS CUI [5])
C0732611 (UMLS CUI [6])
Chronic Kidney Disease | Glomerular Filtration Rate | Disease Affecting Bone remodeling | Paget's disease | Osteogenesis Imperfecta | HIV Infection
Item
chronic kidney disease (calculated gfr <30 ml/min) or a disease known to affect bone turnover (i.e. paget disease, osteogenesis imperfecta, hiv) will be excluded from the study.
boolean
C1561643 (UMLS CUI [1])
C0017654 (UMLS CUI [2])
C0012634 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C0085268 (UMLS CUI [3,3])
C0029401 (UMLS CUI [4])
C0029434 (UMLS CUI [5])
C0019693 (UMLS CUI [6])
Pancreatitis
Item
history of pancreatitis
boolean
C0030305 (UMLS CUI [1])