patients who are 40 years of age or older

patients with confirmed diagnosis of type ii diabetes

patients with 3 or more cvd risk factors or with confirmed/history of cad or history of ischemic stroke

patients who have lab data within 30 days of baseline visit

patients who are willing to return for all follow up visits

patients who are not willing or not able to return to the same hospital within 12 months after enrollment

patients who have life threatening or terminal disease, or are physically unable to make follow up visits every 6 months after enrollment

patients have severe heart failure (new york heart association [nyha] class 3-4)

patients with severe renal deficiency (creatinine clearance less than 30 ml/min)

patients who are not willing to sign informed consent form