ID.1
Item
diagnosis of adult onset ra disease according to revised 1987 american rheumatism association (ara) criteria who are currently or have a documented history of positive for rheumatoid factor (rf) and/or anti-cyclic citrullinated peptide antibody (anti-ccp ab) and who have moderately to severely active ra despite ongoing methotrexate (mtx) therapy
boolean
ID.2
Item
have active ra defined as the presence of at least 8/68 tender and at least 8/66 swollen joints, as determined by the tender joint count and swollen joint count assessment forms
boolean
ID.3
Item
have a screening c-reactive protein (crp) measurement greater than 1.2 times upper limit of normal or erythrocyte sedimentation rate (esr) greater than 28 mm/hr
boolean
ID.4
Item
have a clinically inflamed joint suitable for synovial biopsy procedure
boolean
ID.5
Item
have used an unstable dose of non-steroidal anti-inflammatory drugs (nsaids) within 6 weeks prior to baseline
boolean
ID.6
Item
have used oral corticosteroids at average daily doses of >10 mg/day of prednisone or its equivalent within 6 weeks prior to baseline
boolean
ID.7
Item
have received any parenteral corticosteroid injection within 6 weeks of baseline
boolean
ID.8
Item
have used other disease-modifying anti-rheumatic drugs (dmards) other than mtx, hydroxychloroquine and/or sulfasalazine in the 8 weeks prior to baseline
boolean