Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Age
Item
age between 18 and 75 years
boolean
C0001779 (UMLS CUI [1])
Rheumatoid Arthritis
Item
rheumatoid arthritis according to the american college of rheumatology (acr) criteria 1987 or acr/european liga against rheumatology (eular)2010
boolean
C0003873 (UMLS CUI [1])
Disease activity score 28 joint in rheumatoid arthritis
Item
disease activity score (das) 28 > 2.6
boolean
C2732493 (UMLS CUI [1])
Exclusion Criteria Main
Item
main exclusion criteria:
boolean
C0680251 (UMLS CUI [1,1])
C1542147 (UMLS CUI [1,2])
Subcutaneous administration of treatment Self-injection
Item
prior or other current subcutaneous treatment with self-injection
boolean
C1273555 (UMLS CUI [1,1])
C4296903 (UMLS CUI [1,2])
Biological agents
Item
prior or concomitant treatment with biologics
boolean
C0005515 (UMLS CUI [1])
Medical contraindication Methotrexate treatment
Item
contraindications to mtx treatment
boolean
C1301624 (UMLS CUI [1,1])
C0746573 (UMLS CUI [1,2])
Dermatologic disorder Injection site
Item
history or diagnosis of a dermatological disease at the injection site
boolean
C0037274 (UMLS CUI [1,1])
C2700396 (UMLS CUI [1,2])
Childbearing Potential Contraceptive methods Absent | Gender Partner Childbearing Potential | Gender Contraceptive methods Absent
Item
women with child-bearing potential who do not use a highly effective method of contraception or men who have a partner with child-bearing potential and do not use a contraception during the study and at least 6 months thereafter.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C0682323 (UMLS CUI [2,2])
C3831118 (UMLS CUI [2,3])
C0079399 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])