patient from 45 to 75 years old;

serum level of psa > 4,0 ng / ml;

multiparametric prostate irm, performed before inclusion and which confirm the diagnosis of suspected target;

no opposition of the patient notified in the medical record

patient member in a national insurance scheme.

previous prostate biopsy;

suspicious digital rectal examination;

serum psa > 20,0 ng / ml;

treatment with 5 alpha reductase inhibitor during the last 3 months;

untreated urinary infection