clinically indicated request for spect

ability to undergo at least one of three non-nuclear imaging tests; cmr, ct or stress echocardiography

history of recent symptoms suggestive of myocardial ischemia

high risk for ischemic cardiovascular events

severely reduced systolic function (lv ejection fraction less than 35%)

recent (less than 3 days) acute coronary syndrome including acute myocardial infarction

contraindications to dipyridamole spect including : i)severe reactive airway disease; ii) less than 3 days post myocardial infarction - acute coronary syndrome (mi-acs); iii) high-grade atrioventricular block (av block); iv)allergy to dipyridamole or theophylline; v) caffeine within 12 hours; vi) theophylline use within 48 hours; vii) severe claustrophobia; or viii) women who may be pregnant

kidney dysfunction (i.e estimated glomerular filtration rate (egfr) less than 45)

use of investigational drug or device within 30 days of screening visit