confirmed diagnosis of multiple myeloma with either durie-salmon stage i, ii, or iii or iss stage i, ii or iii, less than 12 months since initiation of systemic therapy

≥8x106 cd34+cells/kg available in cryopreservation in aliquots appropriate for tandem transplants

age: 18-75 years at time of transplantation

kps 70-100%

recovery from complications of prior therapies

gender: there is no gender restriction

diagnosis other than multiple myeloma

chemotherapy or radiotherapy within 8 days of initiating treatment in this study

prior autologous or allogeneic transplantation (except as enrolled into this study)

uncontrolled bacterial, viral, fungal or parasitic infections