ID.1
Item
male and female subjects, 18-65 years of age (females non-child bearing potential in part b)
boolean
ID.2
Item
have laboratory evidence of hcv infection for 6 months, defined by (1) presence of anti-hcv antibody (genotype 1a and 1b infection), or (2)documented hcv rna presence by a sensitive and specific assay and (3 histologic evidence of chc (fibrosis on a standardized histological grading system)
boolean
ID.3
Item
plasma hcv rna of 100,000 iu/ml
boolean
ID.4
Item
hiv 1 and hiv2 ab seronegative
boolean
ID.5
Item
body mass index (bmi) ≤ 35 kg/m2 bmi
boolean
ID.6
Item
treatment naive subjects
boolean
ID.7
Item
contraindications to peginterferon or ribavirin therapy
boolean
ID.8
Item
have evidence of liver cirrhosis, decompensated liver disease, and child-pugh score > 5
boolean
ID.9
Item
have hemoglobinopathies, unstable cardiac disease, history of organ transplant, active malignant disease or uncontrolled type i or ii diabetes
boolean