diabetes mellitus type 2 diagnosed (baseline glycemia > 7,0 mmol/l (126 mg/dl) or overload glycemia > 11,0 mmol/l (198 mg/dl)

on treatment with metformin tablets

patients with at least 2 treated co-morbidities

established dose of metformin > 1.700 mg/day

age > 18 years old

given informed consent

patients not able to take medication orally

according to summary of product characteristics (smpc)

participating in another clinical trial 30 days prior to randomization

any other illness or medical or psychiatric condition, severe and uncontrolled that could interfere in the patient's participation or in the assessment of the study results