a de novo native coronary artery lesions (reference vessel diameter:2.5-3.75 mm)

class i indication to elective percutaneous coronary intervention

stable conditions and no recent acute coronary syndromes

normal baseline values of markers of myocardial damage (creatine kinase, creatine kinase-mb, myoglobin, and troponin i)

able to understand and willing to sign the informed cf

contraindications to des use (clinical history difficult to obtain, expected poor compliance with dapt, non-elective surgery required, increased risk of bleeding

allergy to asa or clopidogrel/prasugrel/ticagrelor, indication for long-term anticoagulation, large vessels, focal lesions)

women of child bearing potential patients must demonstrate a negative pregnancy test performed within 24 hours before ct

indications to des use (small vessels, long lesions diabetes, in-stent restenosis, complex lesions)