age between 18y~80y, with symptomatic coronary disease

at least one lesion length more than 40mm to be treated by overlapping drug-eluting stents in major epicardial coronary vessel

aspirin or clopidogrel intolerance

lesions length less than 40mm, or overlapping stent length less than 40mm

bifurcation lesions need to be treated by two stents

patients with acute coronary syndrome and elevated baseline cardiac enzyme (ck-mb)

left ventricular ejection fraction less than 0.35

baseline estimated gfr less than 30

estimated life time less than one year

refuse to sign the informed consent