chronic hcv infection prior to study enrollment.

screening laboratory result indicating hcv genotype 1-infection.

subject has plasma hcv rna level greater than 10,000 iu/ml at screening.

per local standard, subject is considered to be non-cirrhotic or to have compensated cirrhosis.

history of severe, life-threatening or other significant sensitivity to any drug.

positive test result for hepatitis b surface antigen (hbsag) or anti-human immunodeficiency virus antibody (hiv ab).

prior therapy for the treatment of hcv.

any current or past clinical evidence of child pugh b or c classification of clinical history of liver decompensation including ascites (noted on physical exam), variceal bleeding or hepatic encephalopathy.

any cause of liver disease other than chronic hcv infection.