Age
Item
males and females ≥18 years of age, inclusive
boolean
C0001779 (UMLS CUI [1])
Chronic Hepatitis C Genotype
Item
chronic hcv infection genotype 1 only
boolean
C0524910 (UMLS CUI [1,1])
C0017431 (UMLS CUI [1,2])
Liver Cirrhosis Absent
Item
non-cirrhotic
boolean
C0023890 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Therapy naive | Absence Exposure to Interferon | Absence Exposure to Interferon-alpha | Absence Exposure to Peginterferon alfa-2a | Absence Exposure to Peginterferon alfa-2b | Absence Exposure to Ribavirin | Absence Exposure to Direct Acting Anti-hepatitis C (HCV) Agents | Absence Exposure to Proteases | Absence Exposure to Polymerase Inhibitor
Item
treatment naive subjects with no previous exposure to an interferon formulation (ie, ifnα, pegifnα), ribavirin (rbv) or hcv direct acting antiviral (daa) (protease, polymerase inhibitor, etc.)
boolean
C0919936 (UMLS CUI [1])
C0332197 (UMLS CUI [2,1])
C0332157 (UMLS CUI [2,2])
C3652465 (UMLS CUI [2,3])
C0332197 (UMLS CUI [3,1])
C0332157 (UMLS CUI [3,2])
C0002199 (UMLS CUI [3,3])
C0332197 (UMLS CUI [4,1])
C0332157 (UMLS CUI [4,2])
C0391001 (UMLS CUI [4,3])
C0332197 (UMLS CUI [5,1])
C0332157 (UMLS CUI [5,2])
C0796545 (UMLS CUI [5,3])
C0332197 (UMLS CUI [6,1])
C0332157 (UMLS CUI [6,2])
C0035525 (UMLS CUI [6,3])
C0332197 (UMLS CUI [7,1])
C0332157 (UMLS CUI [7,2])
C4324239 (UMLS CUI [7,3])
C0332197 (UMLS CUI [8,1])
C0332157 (UMLS CUI [8,2])
C0030940 (UMLS CUI [8,3])
C0332197 (UMLS CUI [9,1])
C0332157 (UMLS CUI [9,2])
C1335439 (UMLS CUI [9,3])
C1999216 (UMLS CUI [9,4])
Hepatitis C virus genotype Except Genotype 1
Item
hcv genotype other than genotype 1
boolean
C1148363 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C3532919 (UMLS CUI [1,3])
Liver carcinoma Documented | Liver carcinoma Suspected
Item
documented or suspected hepatocellular carcinoma
boolean
C2239176 (UMLS CUI [1,1])
C1301725 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Decompensated liver disease
Item
evidence of decompensated liver disease
boolean
C4075847 (UMLS CUI [1])
Medical contraindication Peginterferon | Medical contraindication Ribavirin
Item
contraindication(s) to peg/rbv therapy
boolean
C1301624 (UMLS CUI [1,1])
C0982327 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0035525 (UMLS CUI [2,2])