Gender | Age
Item
female patients, >=18 years of age;
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Breast Carcinoma
Item
breast cancer;
boolean
C0678222 (UMLS CUI [1])
CNS disorder Progressive | Status post Radiosurgery | Status post Whole brain radiation therapy | Status post Combined Modality Therapy
Item
cns progression after radio-surgery + whole brain radiotherapy, or whole brain radiotherapy alone;
boolean
C0007682 (UMLS CUI [1,1])
C0205329 (UMLS CUI [1,2])
C0231290 (UMLS CUI [2,1])
C0085203 (UMLS CUI [2,2])
C0231290 (UMLS CUI [3,1])
C1520143 (UMLS CUI [3,2])
C0231290 (UMLS CUI [4,1])
C0009429 (UMLS CUI [4,2])
Measurable lesion Quantity
Item
at least one measurable lesion;
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
ECOG performance status
Item
ecog performance status 0-2.
boolean
C1520224 (UMLS CUI [1])
Systemic therapy Metastatic malignant neoplasm to brain
Item
prior systemic treatment of brain metastases;
boolean
C1515119 (UMLS CUI [1,1])
C0220650 (UMLS CUI [1,2])
Disease Progression | Xeloda
Item
prior disease progression while on xeloda treatment;
boolean
C0242656 (UMLS CUI [1])
C0724419 (UMLS CUI [2])
Malignant Neoplasms | Exception Curative treatment Basal cell carcinoma | Exception Curative treatment Squamous cell carcinoma of skin | Exception Curative treatment Carcinoma in situ of uterine cervix
Item
previous history of cancer (other than curatively treated basal and squamous cell cancer of the skin or in situ cancer of the cervix) in previous 5 years;
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1273390 (UMLS CUI [2,2])
C0007117 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C1273390 (UMLS CUI [3,2])
C0553723 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C1273390 (UMLS CUI [4,2])
C0851140 (UMLS CUI [4,3])
Cardiovascular Disease
Item
clinically significant cardiovascular disease.
boolean
C0007222 (UMLS CUI [1])