Atrial Fibrillation | Anticoagulation Therapy chronic
Item
patients with atrial fibrillation who has been receiving chronic anticoagulation for at least 3 months.
boolean
C0004238 (UMLS CUI [1])
C0003281 (UMLS CUI [2,1])
C0205191 (UMLS CUI [2,2])
Medical contraindication Colchicine | Colchicine allergy
Item
contraindications to colchicine such as allergy/hypersensitivity,
boolean
C1301624 (UMLS CUI [1,1])
C0009262 (UMLS CUI [1,2])
C0571131 (UMLS CUI [2])
Colchicine | Anti-Inflammatory Agents | Adrenal Cortex Hormones | Methotrexate | Antineoplastic Agents | Interleukin-1 Receptor Antagonist | Tumor necrosis factor-alpha inhibitor
Item
receiving colchicine or other anti-inflammatory drugs (such as corticosteroids, methotrexate, anti-neoplastic, interleukin 1-1b antagonist, tumor necrosis factor-alpha inhibitor),
boolean
C0009262 (UMLS CUI [1])
C0003209 (UMLS CUI [2])
C0001617 (UMLS CUI [3])
C0025677 (UMLS CUI [4])
C0003392 (UMLS CUI [5])
C3536785 (UMLS CUI [6])
C1562242 (UMLS CUI [7])
CYP3A4 Inhibitor Strong | CYP3A4 Inhibitor Moderate | Etiology Plasma Colchicine Elevated
Item
receiving food or co-medications such as strong-moderate cytochrome p450 3a4 inhibitors that will result in elevated plasma level of colchicine,
boolean
C3830624 (UMLS CUI [1,1])
C0442821 (UMLS CUI [1,2])
C3830624 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0015127 (UMLS CUI [3,1])
C0032105 (UMLS CUI [3,2])
C0009262 (UMLS CUI [3,3])
C3163633 (UMLS CUI [3,4])
Inflammatory disorder | Lupus Erythematosus, Systemic | Rheumatoid Arthritis | Connective Tissue Diseases | Chronic infectious disease
Item
inflammatory disorders (sle, rheumatoid arthritis, connective tissue disorder) or chronic infection,
boolean
C1290884 (UMLS CUI [1])
C0024141 (UMLS CUI [2])
C0003873 (UMLS CUI [3])
C0009782 (UMLS CUI [4])
C0151317 (UMLS CUI [5])
Kidney Failure Severe | Estimated Glomerular Filtration Rate | Liver Failure Severe | Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
severe renal (egfr< 30ml/min/1.73m2), or liver failure or liver aminotransferase (alt/ast > 2x upper limit of normal),
boolean
C0035078 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C3811844 (UMLS CUI [2])
C0085605 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0151905 (UMLS CUI [4])
C0151904 (UMLS CUI [5])
Moderate cytopenia | Severe cytopenia | Platelet Count measurement | Neutrophil count | Hematological Disease | Myelodysplasia
Item
moderate or severe cytopenias (platelet < 100, neutrophil count < 1.5) or existing blood dyscrasia (e.g., myelodysplasia)
boolean
C1263978 (UMLS CUI [1])
C1263979 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
C0200633 (UMLS CUI [4])
C0018939 (UMLS CUI [5])
C0026985 (UMLS CUI [6])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Absent
Item
pregnant or lactating woman or woman of child bearing age no protected by reliable contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])