Children | Age | Wheezing Episode Quantity
Item
children between 18 months through 3 years who had at least 2 episodes of wheezing prior to enrolment.
boolean
C0008059 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0043144 (UMLS CUI [3,1])
C0332189 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
Skin test positive Airborne allergen | IgE antibody Titer Airborne allergen | Dust mite | Cat | Cockroach | Mouse | Dog | Pollen | Allergy testing
Item
positive skin tests or specific ige antibody titers to at least one of common airborne allergens: dust mite, cat, cockroach, mouse, dog, pollen (all allergy testing can be done at the screening visit at the study site).
boolean
C0542213 (UMLS CUI [1,1])
C0596057 (UMLS CUI [1,2])
C1292069 (UMLS CUI [2,1])
C0475208 (UMLS CUI [2,2])
C0596057 (UMLS CUI [2,3])
C0998367 (UMLS CUI [3])
C0007450 (UMLS CUI [4])
C0009208 (UMLS CUI [5])
C0025914 (UMLS CUI [6])
C0012984 (UMLS CUI [7])
C0032385 (UMLS CUI [8])
C0199747 (UMLS CUI [9])
High risk of Persistent asthma
Item
the child must also fulfill the criteria for high risk of developing persistent asthma by meeting at least one of the following major conditions or 2 of the following minor conditions:
boolean
C0332167 (UMLS CUI [1,1])
C3266628 (UMLS CUI [1,2])
Dermatitis, Atopic | Asthma parental
Item
major criteria: history of atopic dermatitis and/or parental history of asthma.
boolean
C0011615 (UMLS CUI [1])
C0004096 (UMLS CUI [2,1])
C0030551 (UMLS CUI [2,2])
Allergic rhinitis | Wheezing Independent of Common Cold | Eosinophil count
Item
minor criteria: md-diagnosed allergic rhinitis, wheezing unrelated to colds, blood eosinophils above 4%.
boolean
C2607914 (UMLS CUI [1])
C0043144 (UMLS CUI [2,1])
C0332291 (UMLS CUI [2,2])
C0009443 (UMLS CUI [2,3])
C0200638 (UMLS CUI [3])
Systemic disease Severe | Exception Hypersensitivity | Exception Asthma | Seizures | Major Congenital Anomaly | Physical developmental delay | Intellectual delay | Cerebral Palsy | Thoracic Surgical Procedures | Tuberculosis | Primary immune deficiency disorder | Secondary immune deficiency disorder | Heart Disease | Exception Atrial Septal Defect | Exception Hemodynamically insignificant ventricular septal defect | Exception Heart murmur
Item
the child has a severe systemic condition (other than allergy or asthma) including (but not limited to) seizures, major congenital anomalies, physical and intellectual delay, cerebral palsy, chest surgery, tuberculosis, primary or secondary immunodeficiency or cardiac disorder (except a hemodynamically insignificant asd, vsd or heart murmur).
boolean
C0442893 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0020517 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0004096 (UMLS CUI [3,2])
C0036572 (UMLS CUI [4])
C4288779 (UMLS CUI [5])
C0848141 (UMLS CUI [6])
C1839029 (UMLS CUI [7])
C0007789 (UMLS CUI [8])
C0524832 (UMLS CUI [9])
C0041296 (UMLS CUI [10])
C0398686 (UMLS CUI [11])
C0398795 (UMLS CUI [12])
C0018799 (UMLS CUI [13])
C1705847 (UMLS CUI [14,1])
C0018817 (UMLS CUI [14,2])
C1705847 (UMLS CUI [15,1])
C4546215 (UMLS CUI [15,2])
C1705847 (UMLS CUI [16,1])
C0018808 (UMLS CUI [16,2])
Childbirth Weeks of gestation Quantity
Item
the child was born following 35 or less weeks of gestation.
boolean
C1148523 (UMLS CUI [1,1])
C1135241 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Oxygen Received Neonatal period | Requirement Mechanical ventilation
Item
parental report that the child received oxygen for more than 5 days in the neonatal period, or required mechanical ventilation at any time since birth.
boolean
C0030054 (UMLS CUI [1,1])
C1514756 (UMLS CUI [1,2])
C0935562 (UMLS CUI [1,3])
C1514873 (UMLS CUI [2,1])
C0199470 (UMLS CUI [2,2])
Failure to Thrive
Item
the child fails to thrive, defined as crossing of two major growth percentile lines during the last year.
boolean
C0015544 (UMLS CUI [1])
Chronic lung disease of prematurity | Cystic Fibrosis | Chronic lung disease
Item
the child has chronic lung disease of prematurity (cldp), cystic fibrosis or any other chronic lung disease.
boolean
C0006287 (UMLS CUI [1])
C0010674 (UMLS CUI [2])
C0746102 (UMLS CUI [3])
Immunotherapy
Item
the child ever received immunotherapy.
boolean
C0021083 (UMLS CUI [1])
Gammaglobulin Intravenous | Immunosuppressive Agents Intravenous | Exception Adrenal Cortex Hormones Asthma
Item
the child ever received i.v. gammaglobulins or immunosuppressants (other than corticosteroids for asthma).
boolean
C3702062 (UMLS CUI [1,1])
C1522726 (UMLS CUI [1,2])
C0021081 (UMLS CUI [2,1])
C1522726 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0001617 (UMLS CUI [3,2])
C0004096 (UMLS CUI [3,3])
Life threatening acute exacerbation of asthma Requirement Intubation | Life threatening acute exacerbation of asthma Requirement Mechanical ventilation
Item
history of a life-threatening asthma exacerbation which required intubation and mechanical ventilation.
boolean
C4543404 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0021925 (UMLS CUI [1,3])
C4543404 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0199470 (UMLS CUI [2,3])