Urothelial Carcinoma | Exception Micropapillary transitional cell carcinoma
Item
histologic or cytologic diagnosis of urothelial (transitional cell) carcinoma with the exception of micropapillary subtype
boolean
C2145472 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1266012 (UMLS CUI [2,2])
Recurrent disease Advanced Locally | Metastatic/Recurrent Disease | Local Therapy Unsuccessful | Distant metastasis
Item
patients must have recurrent disease (locally advanced or metastatic) that is not amenable to local therapy or newly diagnosed distant metastatic disease
boolean
C0277556 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C1517927 (UMLS CUI [1,3])
C1334739 (UMLS CUI [2])
C1517925 (UMLS CUI [3,1])
C1272705 (UMLS CUI [3,2])
C1269798 (UMLS CUI [4])
Measurable Disease
Item
measurable disease defined by recist v.1.0
boolean
C1513041 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status of 2 or better
boolean
C1520224 (UMLS CUI [1])
Organ function | Bone Marrow function
Item
adequate organ and bone marrow function defined as
boolean
C0678852 (UMLS CUI [1])
C0005953 (UMLS CUI [2,1])
C0031843 (UMLS CUI [2,2])
Cancer Other | Exception Urothelial Carcinoma
Item
other tumor type than urothelial carcinoma
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C2145472 (UMLS CUI [2,2])
CNS metastases
Item
presence or history of cns metastasis
boolean
C0686377 (UMLS CUI [1])
Systemic Chemotherapy | Prior Immunotherapy
Item
prior systemic chemotherapy or immunotherapy (but prior local intravesical chemotherapy or immunotherapy was allowed. and recurrent disease after adjuvant or neoadjuvant cisplatin-based systemic chemotherapy is allowed if the last chemotherapy was administered 1 year or more before the patient enrollment.)
boolean
C1883256 (UMLS CUI [1])
C1514461 (UMLS CUI [2])
Second Primary Cancers | Exception Carcinoma in situ of uterine cervix | Exception Basal cell carcinoma Treated
Item
presence of second primary malignancy (except in situ carcinoma of the cervix or adequately treated basal cell carcinoma of the skin)
boolean
C0751623 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0851140 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0007117 (UMLS CUI [3,2])
C1522326 (UMLS CUI [3,3])
Peripheral sensory neuropathy CTCAE Grades
Item
peripheral sensory neuropathy grade 2 or worse
boolean
C0151313 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Illness Serious | Other medical condition Serious
Item
other serious illness or medical conditions
boolean
C0221423 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C3843040 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])