Non-Insulin-Dependent Diabetes Mellitus Poorly controlled | Hemoglobin A1c measurement | Metformin Dosage
Item
patients with type 2 diabetes mellitus who were inadequately controlled (baseline a1c of 7.0~11.0%)on metformin monotherapy (1500mg metformin)for ≥ 2 months before baseline visit
boolean
C0011860 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
C0474680 (UMLS CUI [2])
C0025598 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
Age
Item
age of 18-80 years
boolean
C0001779 (UMLS CUI [1])
Body mass index
Item
body mass index of 18-40 kg/m2
boolean
C1305855 (UMLS CUI [1])
Diabetes Mellitus, Insulin-Dependent
Item
type 1 of diabetes
boolean
C0011854 (UMLS CUI [1])
Myocardial Infarction | Angina, Unstable | Coronary Artery Bypass Surgery
Item
myocardial infarction, unstable angina, or coronary artery bypass graft within the previous 6 months
boolean
C0027051 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0010055 (UMLS CUI [3])
Congestive heart failure New York Heart Association Classification
Item
congestive heart failure (iii or nyha class iv)
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Liver disease | Liver Cirrhosis | Hepatitis, Chronic
Item
liver disease such as cirrhosis or chronic active hepatitis
boolean
C0023895 (UMLS CUI [1])
C0023890 (UMLS CUI [2])
C0019189 (UMLS CUI [3])
Lactic acidemia
Item
history of lacticacidemia
boolean
C0347959 (UMLS CUI [1])
Antidiabetics Oral | Exception Metformin
Item
use of any oral anti-diabetic drug other than metformin within the 2 months
boolean
C0935929 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0025598 (UMLS CUI [2,2])
Insulin
Item
use of insulin before screening visit
boolean
C0021641 (UMLS CUI [1])
Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
alt or ast >3 times the upper limit of normal range
boolean
C0151905 (UMLS CUI [1])
C0151904 (UMLS CUI [2])
Creatinine measurement, serum
Item
creatinine >1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
Pregnancy | Breast Feeding | Substance Use Disorders | Night shift worker | Laboratory test result abnormal | Medical condition Affecting Completion of clinical trial | Medical condition Affecting Research results
Item
other situation (pregnant or lactating females, history of drug or alcohol abuse, night-shift workers, clinically significant laboratory abnormality on screening or any medical condition that would affect the completion or outcome of the study)
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0038586 (UMLS CUI [3])
C0555008 (UMLS CUI [4])
C0438215 (UMLS CUI [5])
C3843040 (UMLS CUI [6,1])
C0392760 (UMLS CUI [6,2])
C2732579 (UMLS CUI [6,3])
C3843040 (UMLS CUI [7,1])
C0392760 (UMLS CUI [7,2])
C0683954 (UMLS CUI [7,3])